Scintigraphic studies are used in veterinary medicine to image thyroid, parathyroid, adrenal and pancreatic diseases. By far, the most common of these studies is thyroid scintigraphy. Thyroid scintigraphy has been described in a variety of domestic species including feline, canine, equine and avian. Feline scintigraphy has been the most extensively studied. Parathyroid scintigraphy showed promise after an initial case report but further work was disappointing in terms of sensitivity and specificity. Adrenal scintigraphy has been reported but is limited to a case report on a pheochromoctyoma. Somatostatin receptor scintigraphy has also been reported to image a variety of tumors such as paraganglioma, and insulinomas. This presentation will review these applications of scintigraphy to image endocrine disease in dogs and cats.