Hyperthyroid Hints

Peterson M.E. J Endocrinol, 2014. 223(2): p.T97-T114.   Since first discovered just 35 years ago, the incidence of spontaneous feline hyperthyroidism has increased dramatically to the extent that it is now one of the most common disorders seen in middle-aged to … Read More

Bush J.L., Nemanic S. and Gordon J.   Conference Proceedings, (2014). American College of Veterinary Radiology:    Introduction/Purpose: Hyperthyroidism is diagnosed based on clinical signs and elevated serum total thyroxine (TT4) levels. Imaging diagnosis is made with nuclear scintigraphy, and … Read More

Hill KE, Shaw IC. Does exposure to thyroxine-mimics cause feline thyroid hyperplasia? Vet Rec 2014;175:228-229. Hyperthyroidism in cats was first discovered in the late 1970s (Holzworth and others 1980). since then, its incidence has increased from one in 1000 cats … Read More

O’Neill D.G., Church D.B., Mcgreevy P.D., et al. Vet J, 2014.    Improved understanding of absolute and relative prevalence values for common feline disorders could support clinicians when listing differential diagnoses and also assist prioritisation of breeding, research and health … Read More

Stephens M.J., Neill D.G., Church D.B., et al. Vet Rec, 2014.    Feline hyperthyroidism is a commonly diagnosed endocrinopathy that can have a substantial deleterious impact on the welfare of affected cats. This study aimed to estimate the prevalence, associated … Read More

Hanzlicek A.S., Roof C.J., Sanderson M.W., et al.   J Vet Intern Med, 2014. 28(4): p.1221-8.   BACKGROUND: Renal fibrosis is common in progressive kidney disease. Transforming growth factors beta (TGF-beta) are important mediators of all types of fibrosis, including … Read More

Hill K.E., Gieseg M.A., Bridges J., et al.   N Z Vet J, 2014. 62(4): p.208-13.   AIM: To determine the pharmacokinetics of a novel lipophilic formulation of transdermal methimazole compared to oral carbimazole. METHODS: Healthy cats received 5 mg … Read More

Laflamme D. and Gunn-Moore D.   Vet Clin North Am Small Anim Pract, 2014. 44(4): p.761-774.   At least one-third of cats seen by veterinarians are mature, defined as 7 years of age or older, and approximately 13% of cats … Read More

Peterson M.E. and Eirmann L.   Vet Clin North Am Small Anim Pract, 2014. 44(4): p.775-788.   When treating cats with endocrine disease, most veterinarians concentrate on medical or surgical treatments that can be used to manage or cure the … Read More

Williams T.L., Elliott J. and Syme H.M.   J Vet Intern Med, 2014. 28(4): p.1251-5.   BACKGROUND: Iatrogenic hypothyroidism is associated with an increased incidence of azotemia after treatment of hyperthyroidism, and decreased survival time in azotemic hyperthyroid cats. HYPOTHESIS: … Read More

Peterson M. Conference Proceedings, (2014). American College of Veterinary Internal Medicine, Nashville: Hyperthyroidism and chronic kidney disease (CKD) are both common disorders in older cats. Therefore, it should not be surprising that both disorders frequently develop together in the same … Read More

Peterson M.E. and Broome M.R. Conference Proceedings, (2014). American College of Veterinary Internal Medicine, Nashville: Radioactive iodine (131I) provides a simple, effective, and safe treatment for cats with hyperthyroidism. Ideally, treatment with a single dose of 131I restores euthyroidism without … Read More

Williams T.L., Elliott J. and Syme H.M.   Res Vet Sci, 2014. 96(3): p.436-41.   Many hyperthyroid cats develop azotaemic chronic kidney disease (aCKD) following treatment, which has led to the hypothesis that hyperthyroidism might be detrimental to renal function. … Read More

Hickey M.C., Jandrey K., Farrell K.S., et al. J Vet Intern Med, 2014. 28(2): p.319-23.   BACKGROUND: Renal infarcts identified without definitive association with any specific disease process. OBJECTIVE: Determine diseases associated with diagnosis of renal infarcts in cats diagnosed … Read More

Galgano M., Spalla I., Callegari C., et al.   Journal of Veterinary Internal Medicine, 2014. 28(2): p.682-686. A 5-year-old, neutered male domestic shorthair cat was referred for evaluation of suspected hypothyroidism. In the previous 2 months, the owner reported mild … Read More

Rasmussen S.H., Andersen H.H. and Kjelgaard-Hansen M.   Vet Clin Pathol, 2014. 43(1): p.1-3. This letter is written to raise awareness that there may be no clear benefit in the combined measurement of serum total T4 (tT4) and free T4 … Read More

Sangster J.K., Panciera D.L., Abbott J.A., et al.   Journal of Veterinary Internal Medicine, 2014. 28(2): p.465-472.   Background Hyperthyroidism has substantial effects on the circulatory system. The cardiac biomarkers NT-proBNP and troponin I (cTNI) have proven useful in identifying … Read More

Higgs P., Murray J.K. and Hibbert A. J Feline Med Surg, 2014.    Feline hyperthyroidism is commonly diagnosed in general practice. This study assessed the opinions and experiences of UK general practitioners (GPs) regarding the management of feline hyperthyroidism. This … Read More

Boland L.A., Murray J.K., Bovens C.P., et al.   J Feline Med Surg, 2014. 16(8): p.663-670.   The efficacy of radioiodine treatment of feline hyperthyroidism is well established; however, limited information is known about owners’ perceptions or experiences of radioiodine. … Read More

Carter J., Irving A., Bridges J., et al.   N Z Vet J, 2014. 62(1): p.21-9.   Abstract AIMS: To provide an estimate of the prevalence of ocular lesions associated with hypertension in geriatric cats in Auckland, New Zealand and … Read More

Daminet S., Kooistra H.S., Fracassi F., et al.   J Small Anim Pract, 2014. 55(1): p.4-13.   Pharmacological management of feline hyperthyroidism offers a practical treatment option for many hyperthyroid cats. Two drugs have been licensed for cats in the … Read More

Daniel G.B. and Neelis D.A.   Semin Nucl Med, 2014. 44(1): p.24-34.   Thyroid scintigraphy is performed in cats and dogs and has been used to a limited degree in other species such as the horse. Thyroid scintigraphy is most … Read More

Lautenschlaeger I.E., Hartmann A., Sicken J., et al. Vet Radiol Ultrasound, 2013. 54(6): p.666-673. Scintigraphy is currently the reference standard for diagnosing feline hyperthyroidism; however, computed tomography (CT) is more widely available in veterinary practice. The purposes of this prospective … Read More

Van Der Kooij M., Becvarova I., Meyer H.P., et al.   J Feline Med Surg, 2013. 16(6): p.491-498.   The objective of this prospective, multicentre, non-controlled, open-label study was to evaluate the effects of an iodine-restricted food on circulating total … Read More

Higgs P., Murray J. and Hibbert A. Conference Proceedings, (2013). British Small Animal Veterinary Congress: p.1-2 Feline hyperthyroidism is commonly managed with anti­thyroid medication, however, consensus regarding monitoring of treated cats is currently lacking. This study aimed to evaluate how … Read More

Bettencourt A.E., Panciera D.L., Larson M., et al. Conference Proceedings, (2013). American College of Veterinary Radiology, Savannah, GA: p.75   IntroductionlPurpose: Thyroid scintigraphy has been used to diagnose, quantify and characterize disease, and predict treatment outcome in hyperthyroid cats. Scintigraphic … Read More

Peterson M.E.   Journal of feline medicine and surgery, 2013. 15(9): p.765-77.   Clinical challenges: In older cats presenting with clinical features of hyperthyroidism, confirmation of a diagnosis of thyroid disease is usually straightforward. However, the potential for false-negative and … Read More

Reynolds B.S. and Lefebvre H.P.   Journal of feline medicine and surgery, 2013. 15 Suppl 1: p.3-14.   PRACTICAL RELEVANCE: Chronic kidney disease (CKD) is one of the most frequently encountered disorders in cats, having increased in prevalence in recent … Read More

Sabatino B.R., Rohrbach B.W., Armstrong P.J., et al. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 2013. 27(5): p.1049-55. BACKGROUND: Hyperthyroidism is common among older cats, but its pathogenesis remains poorly understood. Siamese and Himalayan cats … Read More

Edinboro C.H., Pearce E.N., Pino S., et al. Journal of feline medicine and surgery, 2013. 15(8): p.717-24. Fluctuations in iodine concentration in food have been suggested as one risk factor for the development of feline hyperthyroidism, an epidemic disease first … Read More

Peterson M.E. Compend Contin Educ Vet, 2013. 35(8): p.E1. Although naturally occurring hypothyroidism is very rare in cats, iatrogenic hypothyroidism is a recognized complication of treatment for hyperthyroidism. However, confirming the diagnosis of hypothyroidism in cats is not generally straightforward. … Read More

Peterson M.E. Compend Contin Educ Vet, 2013. 35(8): p.E3. In older cats presenting with clinical features of hyperthyroidism, confirming the diagnosis of thyroid disease is usually straightforward. However, the potential for false-negative and false-positive results exists with all thyroid function … Read More

Williams T.L., Elliott J., Berry J., et al.   The Journal of small animal practice, 2013. 54(7): p.367-73.   OBJECTIVE: To investigate possible pathophysiological mechanisms (reduced plasma calcitriol concentrations and/or presence of concurrent or masked chronic kidney disease) for hypocalcaemiain … Read More

Broome M.R. and Peterson M.E.   Conference Proceedings, (2013). American College of Veterinary Internal Medicine, Seattle: p.686   Hyperthyroidism develops in cats secondary to 1 or more autonomously functional thyroid adenomas. The progressive thy- rotoxicosis that ensues causes the chronic … Read More

Caney S.M. Journal of feline medicine and surgery, 2013. 15(6): p.494-502. Hyperthyroidism is the most common feline endocrinopathy. Treatment options comprise anti-thyroid medication, iodine-restricted diet, surgical thyroidectomy and radioiodine. One hundred and eleven owners of hyperthyroid cats completed a detailed … Read More

Chciuk K., Behrend E.N., Martin L., et al.   Conference Proceedings, (2013). American College of Veterinary Internal Medicine:   Iatrogenic hypothyroidism following treatment of feline hyperthyroidism can have deleterious effects on renal function. Serum total thyroxine concentration (T4) is commonly … Read More

Williams T., Elliott J. and Syme H.M.   Conference Proceedings, (2013). American College of Veterinary Internal Medicine, Seattle: p.686     Hyperthyroid cats are reported to have reduced blood ionised calcium concentrations (iCa) and elevated plasma parathyroid hormone (PTH) concentrations, … Read More

Bijsmans E.S., Jepson R.E., Chang Y.M., et al. American College of Veterinary Internal Medicine, 2013. p.732-733.   The association between hypertension and feline chronic kid- ney disease (CKD) is well recognised and the prevalence of hypertension in CKD has been … Read More

Williams T.L., Elliott J. and Syme H.M.   Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 2013. 27(3): p.522-9.   BACKGROUND: Hypertension is present in some hyperthyroid cats at diagnosis or can develop after treatment for … Read More

Ramoo S., Bradbury L., Anderson G., et al. Aust Vet J, 2013. 91(4): p.131-136. OBJECTIVE: To evaluate the sedative, respiratory and cardiovascular effects of subcutaneously administered alfaxalone and butorphanol in a group of hyperthyroid cats. DESIGN: A prospective, single-centre observational … Read More

Boretti F.S., Sieber-Ruckstuhl N.S., Schafer S., et al. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 2013. 27(2): p.377-81.   BACKGROUND: Transdermal methimazole is an acceptable alternative to oral treatment for hyperthyroid cats. There are, however, … Read More

Karck J., Von Spiessen L., Rohn K., et al. Tierarztl Prax Ausg K Kleintiere Heimtiere, 2013. 41(1): p.37-45. Objective: The aim of this study was to evaluate whether the degree of renal insufficiency and/or high blood pressure in cats with … Read More

Lamb V., Gray J., Parkin T., et al. The Veterinary Record, 2013. 172(2): p.45. When hyperthyroidism is treated with radioiodine, up to 75 per cent of the injected dose is excreted in the faeces and urine, which poses hazards to … Read More

Menaut P., Connolly D.J., Volk A., et al. The Journal of small animal practice, 2012. 53(12): p.673-8.   OBJECTIVES: To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment. METHODS: Serum natriuretic … Read More

Tschuor F., Zini E., Schellenberg S., et al. Am J Vet Res, 2012. 73(12): p.1925-31.   Objective-To evaluate 4 methods used to measure plasma insulin-like growth factor (IGF) 1 concentrations in healthy cats and cats with diabetes mellitus or other … Read More

Volckaert V., Vandermeulen E., Saunders J.H., et al. J Feline Med Surg, 2012. 14(12): p.889-94.   A successful, euthyroid outcome after radioiodine therapy in hyperthyroid cats ranges from 83% to 95%. Thyroid volume has been reported as one of the … Read More

Bergman P.J. Top Companion Anim Med, 2012. 27(4): p.156-8.   Paraneoplastic syndromes (PNSs) are neoplasm-associated alterations in bodily structure or function or both that occur distant to the tumor. They are an extremely diverse group of clinical aberrations that are … Read More

Peterson M. J Feline Med Surg, 2012. 14(11): p.804-18.   Practical relevance: Since first being reported in the late 1970s, there has been a dramatic increase in the prevalence of hyperthyroidism in cats. It is now recognized worldwide as the … Read More

Boshoven E.W. and Conway T.S. American College of Veterinary Radiologists, 2012. p.96.   Introduction/Purpose: Radioactive Iodine-131 (131I) has long been used for the treatment of patients with hyperthyroidism. Little information is available pertaining to the outcome of such treatments in … Read More

Williams T.L., Elliott J. and Syme H.M. The Journal of small animal practice, 2012. 53(10): p.561-71.   OBJECTIVES: To evaluate calcium and phosphate homeostasis in hyperthyroid cats and determine if plasma parathyroid hormone and fibroblast growth factor-23 are associated with … Read More

Broome M.R. Conference Proceedings, (2012). New York State Veterinary Conference, New York: p.2   Despite more than 30 years of investigation, and strong clinical suspicions of an environmental and/or dietary mechanism, the exact etiology of feline hyperthyroidism remains elusive. The … Read More

Broome M.R. and Peterson M.E. New York State Veterinary Conference, 2012. p.3.   In humans, thyroid nodules are common, occurring in over half of individuals over 50 years of age. Over 95% of these  thyroid nodules are benign, small to … Read More

Forrester S.D., Towell T.L. and Shenoy K. Conference Proceedings, (2012). Veterinary Medical Association, 130th Annual Meeting, Iowa: p.87-91 Production of thyroid hormone requires uptake by the thyroid gland of sufficient amounts of iodine, provided by dietary intake. The only function … Read More

Higgs P. and Hibbert A. The Veterinary record, 2012. 171(9): p.225-6. Over the next few weeks clinicians at the Feline Centre, Langford veterinary Services, University of Bristol, will be contacting every veterinary practice across the UK to invite them to … Read More

Peterson M.E. and Broome M.R. Conference Proceedings, (2012). ECVIM, Maastricht, Netherlands:   Thyroid scintigraphy provides valuable information regarding both thyroid anatomy and physiology and plays an integral role in the diagnosis, staging, and management of feline thyroid disease. In this … Read More

The Veterinary Record, 2012. 171(6): p.143-4. Current understanding of feline hyperthyroidism, as well as different approaches to treatment and management, were discussed at a symposium held in Barcelona in May this year. Called ‘the rise and fall of thyroxin’, the … Read More

Smith R.R., Mayhew P.D. and Berent A.C. Journal of the American Veterinary Medical Association, 2012. 241(3): p.368-72.   CASE DESCRIPTION: A 9-year-old castrated male domestic shorthair cat was examined because of hypertension that persisted after resolution of the patient’s hyperthyroidism. … Read More

Luis Fuentes V. Journal of feline medicine and surgery, 2012. 14(7): p.459-70.   PRACTICAL RELEVANCE: Feline arterial thromboembolism (ATE) is a common but devastating complication of myocardial disease, often necessitating euthanasia. A combination of endothelial dysfunction and blood stasis in … Read More

Metzger F.L. and Rebar A.H. The Veterinary clinics of North America. Small animal practice, 2012. 42(4): p.615-29, v.   Routine monitoring of clinicopathologic data is a critical component in the management of older patients because blood and urine testing allows … Read More

Norrgran J., Jones B., Lindquist N.G., et al. Arch Environ Contam Toxicol, 2012. 63(1): p.161-8.   The incidence of cats being diagnosed with feline hyperthyroidism (FH) has increased greatly since it was first described in 1979. The cause of FH … Read More

Scott-Moncrieff J.C. The Veterinary clinics of North America. Small animal practice, 2012. 42(4): p.707-25, vi-vii.   The effects of age, concurrent illness, and administered medications complicate diagnosis of thyroid dysfunction in geriatric patients. Interpretation of thyroid hormone testing should take … Read More

Yu S., Wedekind K.J., Burris P.A., et al. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: Hyperthyroidism is a common disease in old cats. Excessive production of thyroid hormones is the hallmark of the disease. Three main treatments for … Read More

Sabatino B.R., Kirk C.A., Rohrbach B.W., et al. Conference Proceedings, (2012). American College of Veterinary Internal Medicine, New Orleans: p.754-755   Hyperthyroidism is common among older cats, but its pathogenesis remains poorly understood. Siamese and Himalayan cats have a reduced … Read More

Branter E., Drescher N., Padilla M., et al. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine, 2012. 26(3): p.582-8.   BACKGROUND: Reversible antioxidant depletion is found in hyperthyroid humans, and antioxidant depletion increases the risk of … Read More

Daniel G. Conference Proceedings, (2012). American College of Veterinary Internal Medicine, New Orleans: p.700-702   Scintigraphic studies are used in veterinary medicine to image thyroid, parathyroid, adrenal and pancreatic diseases. By far, the most common of these studies is thyroid … Read More

Peterson M.E. and Broome M.R. Conference Proceedings, (2012). American College of Veterinary Internal Medicine, New Orleans: p.754   Thyroid scintigraphy provides valuable information regarding both thyroid anatomy and physiology and plays an integral role in the diagnosis, staging, and management … Read More

Vieira A.B., Castro M., Salomao M., et al. Conference Proceedings, (2012). American College of Veterinary Internal Medicine, New Orleans: p.755   Non-thyroidal illnesses, such as chronic kidney disease, are one of the factors that can affect total thyroxine and hinder … Read More

Williams T.L., Elliott J. and Syme H. Conference Proceedings, (2012). American College of Veterinary Internal Medicine, New Orleans: p.752-754   IH is reported to increase the incidence of azotemia in hyperthyroid cats following treatment. IH is also associated with a … Read More

Ramspott S., Hartmann K., Sauter-Louis C., et al. J Feline Med Surg, 2012. 14(4): p.262-6.   Adrenal function may be altered in animals with hyperthyroidism. The aim of the study was to assess adrenal function of hyperthyroid cats (n = … Read More

Combes A., Vandermeulen E., Duchateau L., et al. Vet Radiol Ultrasound, 2012. 53(2): p.210-216.   Feline hyperthyroidism is potentially associated with exaggerated responsiveness of the adrenal gland cortex. The adrenal glands of 23 hyperthyroid cats were examined ultrasonographically and compared … Read More

Guo W., Park J.S., Wang Y., et al. Environ Toxicol Chem, 2012. 31(2): p.301-6.   Polybrominated diphenyl ethers (PBDEs) are brominated flame retardants that act as endocrine disruptors, affecting thyroid hormone homeostasis. As a follow-up to a recent study showing … Read More

Jaillardon L., Burger M. and Siliart B. The Veterinary record, 2012. 170(6): p.155. HYPERTHYROIDISM is a common endocrine disorder in old cats (Edinboro and others 2004). Thyrotoxicosis induces an increased catabolism with reduced fat and muscle mass despite the increased … Read More

Mensching D.A., Slater M., Scott J.W., et al. J Toxicol Environ Health A, 2012. 75(4): p.201-12.   The role of polybrominated diphenyl ethers (PBDE) was investigated in the occurrence of feline hyperthyroidism (FH) by evaluating 15 PBDE congeners in serum … Read More

Heinrich N.A., Mckeever P.J. and Eisenschenk M.C. Vet Dermatol, 2011. 22(6): p.511-20.   Ciclosporin is an immunosuppressive drug that has been used to treat allergies and other immune-mediated diseases in cats, dogs and humans. Information about the adverse effects of … Read More

Hill K.E., Gieseg M.A., Kingsbury D., et al. J Vet Intern Med, 2011. 25(6): p.1357-65.   BACKGROUND: Previous studies on transdermal methimazole have used pluronic lecithin organogel as the vehicle. This might not be the most suitable vehicle for a … Read More

Chapman S.F. Homeopathy, 2011. 100(4): p.270-4.   Hyperthyroidism is a frequent veterinary problem, particularly in elderly cats. Homeopathic treatment and other integrative modalities were provided for four hyperthyroid cats whose owners did not want conventional treatment. Symptomatic homeopathic treatment with … Read More

Peterson M.E., Broome M.R. and Robertson J.E. Conference Proceedings, (2011). European College of Veterinary Internal Medicine, Sevilla, Spain: p.1   Free thyroxine (fT4) is the unbound biologically active fraction of total thyroxine (TT4). The pituitary-thyroid axis functions to maintain fT4 … Read More

Wakeling J., Elliott J. and Syme H. J Vet Intern Med, 2011. 25(5): p.1057-65.   BACKGROUND: In humans, subclinical hyperthyroidism is diagnosed when serum thyroid hormone concentrations are within the reference range but thyroid stimulating hormone (TSH) concentration is subnormal. … Read More

Araujo A.S., Seibel F.E., Oliveira U.O., et al. Cell Biochem Funct, 2011. 29(5): p.408-13.   Thyroid hormones modulate haemoglobin and reactive oxygen species (ROS) production, leading to antioxidant changes. This study evaluated the antioxidant response to ROS in erythrocytes in … Read More

Peterson M.E. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: p.98-100   The thioureylene class of antithyroid drugs, which includes methimazole and carbimazole, are most commonly used drugs for treatment of cats with hyperthyroidism. However a variety of other … Read More

Peterson M.E.   Conference Proceedings, (2011). American College of Veterinary Internal Medicine: p.101-103   Hyperthyroidism and chronic kidney disease (CKD) are both common disorders in older cats. Therefore, it should not be surprising that both disorders frequently develop together in … Read More

Gallagher A.E. and Panciera D.L. J Feline Med Surg, 2011. 13(6): p.441-7.   Iopanoic acid is an iodine containing oral cholecystographic agent that has been used to treat hyperthyroidism in humans and has recently been evaluated in an experimental model … Read More

Harley L.S., Peterson M.E., Langston C.E., et al. Conference Proceedings, (2011). American College of Veterinary Internal Medicine:   Although it is well established that concurrent chronic kidney disease (CKD) develops in about 30% of hyperthyroid cats, no one has reported … Read More

Melendez L. and Al-Murrani S. Conference Proceedings, (2011). American College of Veterinary Internal Medicine:   Hyperthyroidism is a disorder resulting from the excessive production and secretion of T4 and T3 by the thyroid gland. Although the disorder and its pathological … Read More

Melendez L.D., Yamka R.M. and Burris P.A. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: We have shown previously that restriction of dietary iodine (I) is a safe and effective method for decreasing serum thyroxine concentrations (TT4) in cats … Read More

Oman R. and Lunn K.F. Conference Proceedings, (2011). American College of Veterinary Internal Medicine:   Radioactive iodine (131I) is a widely used treatment for feline hyperthyroidism. Prior to 131I administration, many cats receive methimazole therapy. It has been suggested that … Read More

Peterson M.E. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: p.95-97   The diagnosis of hyperthyroidism and hypothyroidism in cats is primarily based on a constellation of typical clinical features, including the cat’s signalment, history, clinical signs, and physical … Read More

Peterson M.E. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: p.104-106   Most hyperthyroid cats, at least in the early stages of their disease, can be readily controlled with antithyroid drugs. Similarly, most cats with mild to moderate hyperthyroidism … Read More

Shiguang Y., Wedekind K.J., Burris P.A., et al. Conference Proceedings, (2011). American College of Veterinary Internal Medicine, Denver:   Hyperthyroidism is a common disease in old cats. Excessive production of thyroid hormones is the hallmark of the disease. Three main … Read More

Van Der Kooij M., Becvarova I., Meijer H.P., et al. Conference Proceedings, (2011). ECVIM: p.EN-16 Feline hyperthyroidism is one of the most common endocrine disorders in middle-aged and elderly cats. Currently, three treatment options are available: (i) anti-thyroid medication, (ii) … Read More

Ward C.R. Conference Proceedings, (2011). American College of Veterinary Internal Medicine: p.500   Hyperthyroidism is the most common endocrinopathy in cats, affecting a large percentage of middle to older aged cats in the U.S. Since its recognition as a clinical … Read More

Williams T.L., Elliott J. and Syme H.M. Conference Proceedings, (2011). American College of Veterinary Internal Medicine:   FGF-23 is secreted by osteocytes and osteoblasts in response to hyperphosphatemia. FGF-23 enhances phosphaturia and is postu- lated to have a central role … Read More

Bojanic K., Acke E. and Jones B. N Z Vet J, 2011. 59(3): p.115-22.   Congenital hypothyroidism is a rare and underdiagnosed congenital endocrine disorder in dogs and cats and the true incidence is unknown. The disorder may cause a … Read More

Graves T.K. Top Companion Anim Med, 2011. 26(2): p.45-51.   Although veterinary clinicians commonly rely on panels of laboratory tests with individual results flagged when abnormal, care should be taken in interpreting normal test results as well. There are several … Read More

Xu L., Cui P.C., Chen Z.F., et al. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2011. 46(4): p.331-5.   OBJECTIVE: To evaluate the biomechanical characteristics of the decellularized laryngeal scaffold. METHODS: Ten Chinese adult dogs were … Read More

Connolly D.J., Hezzell M.J., Fuentes V.L., et al. J Vet Cardiol, 2011. 13(1): p.13-9.   OBJECTIVES: To evaluate whether the addition of a protease inhibitor (PI) to feline plasma improves the temporal stability of N-terminal pro-B-type natriuretic peptide (NT-proBNP). ANIMALS, … Read More

Gallagher B., Mooney C. and Graham P. Conference Proceedings, (2011). British Small Animal Veterinary Association (BSAVA) Congress, Scientific Proceedings, Birmingham: p.457 Since 2008, there have been two licenced oral anti-thyroid medications for treating feline hyperthyroidism in the UK; Felimazole (Dechra … Read More

Altay U.M., Skerritt G.C., Hilbe M., et al. J Am Anim Hosp Assoc, 2011. 47(2): p.89-97.   Sixteen cats with cerebrovascular disease confirmed via histology to be of nontraumatic and nonneoplastic origins are described. In addition, the anatomy of the … Read More

Cook A.K., Suchodolski J.S., Steiner J.M., et al. J Small Anim Pract, 2011. 52(2): p.101-6.   OBJECTIVES: To determine the prevalence of hypocobalaminaemia in cats with moderate to severe hyperthyroidism and to investigate the relationship between cobalamin status and selected … Read More

Gunn-Moore D.A. Top Companion Anim Med, 2011. 26(1): p.17-24.   Increasing numbers of cats are living to become elderly and they commonly develop behavioral changes. The objectives of this article are to consider the possible causes and prevalence of behavioral … Read More

Jepson R.E. J Feline Med Surg, 2011. 13(1): p.25-34.   PRACTICAL RELEVANCE: the increased availability of indirect blood pressure monitoring devices in clinical practice over the past decade has highlighted the significance of systemic hypertension in the feline population. Without … Read More

Stepien R.L. J Feline Med Surg, 2011. 13(1): p.35-43.   PRACTICAL RELEVANCE: the clinical importance of feline hypertension has been recognised for many years and most feline practitioners are quite familiar with this syndrome. Once systemic hypertension is identified, long-term … Read More

Tolbert M.K. and Ward C.R. Compend Contin Educ Vet, 2010. 32(12): p.E1-6.   In human medicine, thyroid storm is a well-recognized condition of acute thyrotoxicosis in which the patient’s metabolic, thermoregulatory, and cardiovascular mechanisms are overwhelmed by excessive circulating levels … Read More

Devictoria T. Veterinary Technician, 2010. 31 (11): p.5.   In clinical practice, middle-aged to older cats often present with classic signs of hyperthyroidism, characterized by rapid weight loss (to the point of cachexia) despite a ravenous appetite. Affected cats can … Read More

Knowles S., Uhl E.W., Blas-Machado U., et al. J Vet Diagn Invest, 2010. 22(6): p.1010-1013.   A 7-year-old spayed female domestic shorthair feline presented with tachycardia and was later euthanized due to a declining condition. On gross examination, the thoracic … Read More

Mathie R.T., Baitson E.S., Hansen L., et al. Homeopathy, 2010. 99(4): p.243-8.   INTRODUCTION: The peer-review literature contains no controlled clinical research of homeopathy in cats and very little in dogs. MAIN OBJECTIVE: To collect clinical outcomes data systematically from … Read More

Edinboro C.H., Scott-Moncrieff J.C. and Glickman L.T. J Feline Med Surg, 2010. 12(9): p.672-9.   ARTICLE RATIONALE: Since the late 1970s, there has been a significant increase in the prevalence of feline hyperthyroidism (FH). It is now recognized worldwide as … Read More

Longhofer S., Martin-Jimenez T. and Soni-Gupta J. Vet Ther, 2010. 11(3): p.E1-7.   Methimazole (thiamazole) is an antithyroid drug commonly used to treat feline hyperthyroidism. It is routinely given twice daily. Carbimazole is a methimazole derivative that is rapidly metabolized … Read More

Wallack S., Metcalf M., Skidmore A., et al. Vet Radiol Ultrasound, 2010. 51(5): p.554-560.   Feline hyperthyroidism is a common endocrine disorder. A single dose of 148 MBq (4 mCi) 131I is 95–98% effective for the treatment of hyperthyroidism in cats; however, … Read More

Williams T.L., Elliott J. and Syme H.M. Conference Proceedings, (2010). American College of Veterinary Internal Medicine, Anaheim p.684   IH is reported to occur in some cats following treatment of hyper- thyroidism (HTH). Hypothyroidism reduces GFR in other species, therefore … Read More

Blois S.L., Dickie E.L., Kruth S.A., et al. J Feline Med Surg, 2010. 12(8): p.637-42.   The objective of this retrospective study was to characterize a population of cats from a tertiary care center diagnosed with multiple endocrine disorders, including … Read More

Wedekind K.J., Blumer M.E., Huntington C.E., et al. J Anim Physiol Anim Nutr (Berl), 2010. 94(4): p.527-39.   The purpose of this study was to determine the iodine (I) requirement in adult cats. Forty-two healthy euthyroid cats (1.6-13.6 years old) … Read More

Williams T., Peak K., Brodbelt D., et al. Journal of Veterinary Internal Medicine, 2010. 24(4): p.863-869. Hyperthyroidism is the most frequently diagnosed endocrinopathy of cats. There are few studies that examine the long-term survival of cats with hyperthyroidism, and most … Read More

Williams T.L., Elliott J. and Syme H.M. J Vet Intern Med, 2010. 24: p.1086-1092.   Background: Iatrogenic hypothyroidism can occur after treatment of hyperthyroidism, and is correlated with a reduced glomerular filtration rate in humans and dogs. Hypothesis: Cats with … Read More

Klein A., Pace C., Elliott J., et al. Conference Proceedings, (2010). American College of Veterinary Internal Medicine, Anaheim: p.730 The cardiac biomarkers N-terminal-pro-Brain Natriuretic Peptide (NT-pro-BNP) and N-terminal -pro-Atrial Natriuretic Peptide (NT-pro-ANP) have been shown to be of value in … Read More

Morrison J., Jergens A., Deitz K., et al. Conference Proceedings, (2010). American College of Veterinary Internal Medicine, Anaheim: p.744-745   Hyperthyroidism is a common endocrine disorder in middle aged to older cats. Therapy with I-131 is considered to be curative … Read More

Morrison J., Jergens A., Deitz K., et al. Conference Proceedings, (2010). American College of Veterinary Internal Medicine, Anaheim: p.745   Hyperthyroidism is one of the most common endocrine disorders in middle aged to older cats. Renal disease may be masked … Read More

Ward C.R., Windham W.R. and Dise D. Am J Vet Res, 2010. 71(6): p.643-8.   OBJECTIVE: To evaluate alterations in ligand-stimulated activity of G proteins in thyroid gland cells of hyperthyroid cats. SAMPLE POPULATION: Membranes of thyroid gland cells isolated … Read More

Barberet V., Baeumlin Y., Taeymans O., et al. Vet Radiol Ultrasound, 2010. 51(3): p.324-30.   Ultrasonography is useful for assessing the morphology of the thyroid gland in hyperthyroid cats. Our aim was to describe the ultrasonographic changes of the thyroid … Read More

Lee W.R., Pease A.P. and Berry C.R. Vet Radiol Ultrasound, 2010. 51(2): p.182-5.   Administration of iodinated contrast medium interferes with iodide uptake in the human thyroid gland and compromises diagnostic thyroid scintigraphy and radioiodine treatment for 4-6 weeks. However, … Read More

Blois S.L., Abrams-Ogg A.C., Mitchell C., et al. J Feline Med Surg, 2010. 12(2): p.156-60.   A 12-year old, castrated male domestic shorthair cat presented with a 2-year history of poor hair coat, seborrhea, generalized pruritus and otitis externa. Low … Read More

Wakeling J. Can Vet J, 2010. 51(1): p.33-4.   Thyroid stimulating hormone (TSH) measurement is routinely used for the diagnosis of thyroid disease in humans and dogs, but measurement of feline TSH is not routinely performed because a commercial feline … Read More

Peterson M.E. and Broome M.R. Conference Proceedings, (2010). American College of Veterinary Internal Medicine, Anaheim: p.627-629   Since hyperthyroidism was first reported 31 years ago, the prevalence of thyroidal nodules and the associated hyperthyroid state has been detected at an … Read More

Frenais R., Rosenberg D., Burgaud S., et al. J Small Anim Pract, 2009. 50(10): p.510-5.   OBJECTIVE: Evaluation of efficacy and safety of a novel controlled-release formulation of carbimazole in feline hyperthyroidism. METHODS: A multicentre, self-controlled study in 44 client-owned … Read More

Le Traon G., Burgaud S. and Horspool L.J. Conference Proceedings, (2009). European College of  Veterinary Internal Medicine – Companion Animals: p.269 Hyperthyroid cats may become (transiently) hypothyroid following 131I radiotherapy or surgical thyroidectomy. Oral supplementation with L-thyroxine (L-T4) may be … Read More

Rutland B.E., Nachreiner R.F. and Kruger J.M. J Vet Intern Med, 2009. 23(5): p.1025-30.   BACKGROUND: Methimazole suppresses thyroid hormone synthesis and is commonly used to treat feline hyperthyroidism. The degree of variation in thyroid hormone concentrations 24 hours after … Read More

Van Hoek I., Meyer E., Duchateau L., et al. J Vet Intern Med, 2009. 23(5): p.1031-7.   BACKGROUND: Retinol-binding protein (RBP) is suggested as a clinically useful marker of renal function in cats. HYPOTHESIS: Serum and urinary RBP concentrations in … Read More

Tolbert K., Brown H.M., Rakich P.M., et al. J Feline Med Surg, 2009. 11(8): p.717-9.   A 5-year-old spayed female cat was evaluated for hyperthyroidism based on an elevated free thyroxine (T(4)) measurement and bilaterally enlarged symmetric subcutaneous masses in … Read More

Van Hoek I.M., Lefebvre H.P., Paepe D., et al. J Feline Med Surg, 2009. 11: p.1028-1030.   The study investigated plasma clearance of exogenous creatinine (PECCT), exo-iohexol (PexICT) and endo-iohexol (PenICT) in six healthy cats, four cats with chronic kidney … Read More

Wakeling J., Everard A., Brodbelt D., et al. J Small Anim Pract, 2009. 50(8): p.406-14.   OBJECTIVES: Previous studies of cats in the USA and New Zealand have identified a number of risk factors for the development of hyperthyroidism including … Read More

Pressler B.M., Robarge M.E. and Anderson K.I. Am J Vet Res, 2009. 70(7): p.869-78.   OBJECTIVE: To partially characterize the cDNA, amino acid sequence, and tertiary structure of feline myeloperoxidase, describe its cellular location in mature granulocytes, and determine whether … Read More

Schaefer D.M.W., Priest H., Stokol T., et al. Veterinary Clinical Pathology, 2009. 38(2): p.194-200.   Abstract: A 17-year-old domestic shorthaired cat was presented to the Cornell University Hospital for Animals for recheck of hyperthyroidism previously treated with radioiodine. Marked agglutination … Read More

Wakeling J., Elliott J., Petrie A., et al. Am J Vet Res, 2009. 70(6): p.741-9.   OBJECTIVE: To compare concentrations of urinary iodide (UI) in euthyroid and untreated hyperthyroid cats. ANIMALS: 118 euthyroid and 88 hyperthyroid client-owned cats from 2 … Read More

Morrow L.D., Adams V.J., Elliott J., et al. Conference Proceedings, (2009). American College of Veterinary Internal Medicine:   Hypertension and azotemic chronic kidney disease (aCKD) can be diagnosed concurrently with hyperthyroidism and have also been detected after initiation of treatment. … Read More

Boretti F.S., Sieber-Ruckstuhl N.S., Gerber B., et al. Journal of Feline Medicine & Surgery, 2009. 11(4): p.286-292.   To relate thyroid size to routine blood parameters and T4 status the ventral neck of 161 cats with clinical signs consistent with … Read More

Downers K. Conference Proceedings, (2009). Central Veterinary Conference, Baltimore: p.1-2   When hyperthyroidism was first reported In cats as a disease entity approximately 25 years ago, the majority of cases were advanced. The cats were thin, aggressive, polyuric, polydipsic, polyphaglc … Read More

Iglesias P. and Diez J.J. Eur J Endocrinol, 2009. 160(4): p.503-15.   Thyroid hormones (TH) are essential for an adequate growth and development of the kidney. Conversely, the kidney is not only an organ for metabolism and elimination of TH, … Read More

Lynn A., Dockins J.M., Kuehn N.F., et al. J Small Anim Pract, 2009. 50(3): p.147-50.   An eight-year-old domestic shorthair cat was evaluated because of dyspnoea secondary to pleural effusion. Ultrasound examination identified a large anechoic cyst-like structure in the … Read More

Norsworthy G.D. Journal of Feline Medicine & Surgery, 2009. 11(6): p.525-525.   I would like to compliment the authors in devising an objective comparison of the two thyroid palpation techniques. My only concern with the study is the experience factor. … Read More

Gallagher A.E. and Panciera D.L. J Feline Med Surg, 2009. 11(2): p.69-75.   The purpose of this study was to evaluate the safety and effect of iopanoic acid in 13 cats with hyperthyroidism induced by daily subcutaneous administration of 25microg/kg … Read More

Harvey A.M., Hibbert A., Barrett E.L., et al. Journal of Feline Medicine & Surgery, 2009. 11(2): p.96-106.   The aim of this study was to characterise the scintigraphic findings in a large population of hyperthyroid cats in order to determine … Read More

Van Hoek I. and Daminet S. General and Comparative Endocrinology, 2009. 160(3): p.205-215.   Thyroidal status affects kidney function already in the embryonic stage. Thyroid hormones influence general tissue growth as well as tubular functions, electrolyte handling and neural input. … Read More

Kooistra H.S., Galac S., Buijtels J.J., et al. Horm Res, 2009. 71 Suppl 1: p.144-7.   BACKGROUND: Several endocrine disorders that affect humans also occur as endocrinopathies in companion animals. Spontaneous endocrine disorders in animals may provide valuable information for … Read More

Van Hoek I., Lefebvre H.P., Peremans K., et al. Domest Anim Endocrinol, 2009. 36(1): p.45-56.   Hyperthyroidism can mask co-existing chronic kidney disease (CKD). Previous studies showed that post-treatment renal azotemia can be predicted by pre-treatment assessment of glomerular filtration … Read More

Kupryianchyk D., Hovander L., Jones B., et al. Organohalogen Compounds, 2009. 71: p.002720-002725.   Feline hyperthyroidism has been observed to increase all over the world since the end of 1970s. It has been suggested that increased risk of developing hyperthyroidism … Read More

Paepe D., Smets P., Van Hoek I., et al. Journal of Feline Medicine & Surgery, 2008. 10(6): p.558-565.   Thyroid gland palpation is an important aid for diagnosing feline hyperthyroidism in an early stage to prevent development of deleterious complications. … Read More

Henik R.A., Stepien R.L., Wenholz L.J., et al. Journal of Feline Medicine & Surgery, 2008. 10(6): p.577-582.   [beta]-Adrenergic blockers, particularly atenolol, are often recommended for the tachycardia and hypertension that accompany hyperthyroidism; however, the effects of monotherapy with atenolol … Read More

Traas A.M., Abbott B.L., French A., et al. J Vet Intern Med, 2008. 22(6): p.1427-31.   Two male littermate kittens (Kitten A and B) were examined at 14 weeks of age because of straining to defecate in the litter box. … Read More

Peremans K., Vandermeulen E., Van Hoek I., et al. J Feline Med Surg, 2008. 10(5): p.460-5.   Absorbed thyroid dose and effective half-life were determined in 46 hyperthyroid cats after treatment with a low dose (mean 111MBq) of radioiodine intravenously. … Read More

De Wet C.S., Mooney C.T., Thompson P.N., et al. J Feline Med Surg, 2008. p.1-7.   A study was conducted to determine the prevalence of and potential risk factors for feline hyperthyroidism in Hong Kong. Serum total thyroxine (T(4)) was … Read More

Lapointe C., Belanger M., Dunn M., et al. Journal of Veterinary Internal Medicine, 2008. 22(5): p.1103-1110.   Hyperthyroid cats are at risk of developing azotemic chronic kidney disease (CKD) and diagnostic tools currently used to screen for CKD in hyperthyroid … Read More

Bailiff N.L., Westropp J.L., Nelson R.W., et al. Vet Clin Pathol, 2008. 37(3): p.317-22.   BACKGROUND: It has been suggested that diseases that promote isosthenuria predispose to urinary tract infections because of a lack of the common bacteriostatic properties present … Read More

Van Hoek I., Lefebvre H.P., Kooistra H.S., et al. J Vet Intern Med, 2008. 22(4): p.879-85.   BACKGROUND: Glomerular filtration rate (GFR) can be measured by clearance methods of different markers showing discrepancies and different reproducibility in healthy cats. Studies … Read More

R. Frenais, S. Burgaud and L. J. I. Horspool Journal of Veterinary Pharmacology and Therapeutics, 2008. 31(3): p.213-219.   FrÈnais, R., Burgaud, S., Horspool, L. J. I. Pharmacokinetics of controlled-release carbimazole tablets support once daily dosing in cats. J. Vet. … Read More

Wakeling J., Moore K., Elliott J., et al. J Small Anim Pract, 2008. 49(6): p.287-94.   OBJECTIVES: In cats with concurrent hyperthyroidism and non-thyroidal illnesses such as chronic kidney disease, total thyroxine concentrations are often within the laboratory reference range … Read More

Donaldson D., Billson F.M., Scase T.J., et al. J Small Anim Pract, 2008. 49(6): p.306-9.   A six-month-old, female, domestic shorthair cat was presented with a history of failure to grow and bilateral corneal opacity caused by corneal oedema. Congenital … Read More

G. Giannoulopoulos Journal of Small Animal Practice, 2008. 49(6): p.319-319. In the March 2007 issue of JSAP, Niessen and others (2007) reported on a case of generalised lymphadenomegaly associated with methimazole treatment, in a hyperthyroid cat. The owner of the … Read More

Van Hoek I., Meyer E., Duchateau L., et al. Conference Proceedings, (2008). American College of Veterinary Internal Medicine-PROC. 26TH ACVIM FORUM, San Antonia, TX: p.731 Retinol binding protein (RBP) is a marker of renal tubular dam- age that is variably … Read More

Wakeling J., Elliott J. and Syme H. Journal of Veterinary Internal Medicine, 2008. 22(3): p.725. Hyperthyroidism is a common disease of older cats and is insidious in onset. In a retrospective study most hyperthyroid cats were found to have had … Read More

Riensche M.R., Graves T.K. and Schaeffer D.J. Journal of Feline Medicine & Surgery, 2008. 10(2): p.160-166.   To determine if routine pre-treatment clinical data can be used to predict the development of overt renal insufficiency following treatment of feline hyperthyroidism, … Read More

Kerry S. Vet Rec, 2008. 162(9): p.287-8.   In summary, the results of this study demonstrated high levels of PBDEs in cats and that fish-flavoured cat foods contained higher levels of PBDEs than other feeds. The level of PBDEs was … Read More

Vandermeulen E., Van Hoek I., De Sadeleer C., et al. J Vet Intern Med, 2008. 22(2): p.266-72.   BACKGROUND: Chronic kidney failure is frequently seen in middle-aged and elderly cats. 51Chromium-ethylene diaminic tetraacetic acid (51Cr-EDTA) clearance and single blood sample … Read More

Butterton S. Vet Rec, 2008. 162(7): p.224. SIR, – A client with a hyperthyroid cat turned up the other day demanding that a blood test for polybrominated diphenyl ethers (PBDEs) be carried out on her animal. She had just learned … Read More

Rosenburg D., Frenais R., Fornel-Thibaud P., et al. Conference Proceedings, (2008). Proceedings of the British Small Animal Veterinary Association Annual Congress: p.488   Carbimazole and its active metabolite methimazole are the standard medical treatment for hyperthyroidism in cats. Most effective … Read More

Van Dijl I.C. and Hof A.J. Tijdschr Diergeneeskd, 2008. 133(2): p.54-62.   Feline hyperthyroidism can be treated by thyroidectomy, antithyroid drugs, or radioactive iodine-131 (131I). The aim of this retrospective study was to evaluate the treatment of 83 hyperthyroid cats … Read More

Van Hoek I., Daminet S., Notebaert S., et al. J Immunol Methods, 2008. 329(1-2): p.208-13.   The presence of low molecular weight retinol binding protein (RBP) in urine reflects tubular damage. Therefore, RBP has been used as a renal marker … Read More

Van Hoek I., Lefebvre H.P., Croubels S., et al. Conference Proceedings, (2008). American College of Veterinary Internal Medicine-PROC. 26TH ACVIM FORUM, San Antonia, TX: p.797 Measurement of glomerular filtration rate (GFR) in cats allows detection of a decreased kidney function … Read More

Berent A.C., Drobatz K.J., Ziemer L., et al. J Vet Intern Med, 2007. 21(6): p.1217-23.   BACKGROUND: The clinical significance of high serum concentration or activity of markers of liver damage in cats with hyperthyroidism is unknown. OBJECTIVE: To evaluate … Read More

Boag A.K., Neiger R., Slater L., et al. Vet Rec, 2007. 161(21): p.711-5.   Hyperthyroidism is a common endocrinopathy of older cats and is associated with an increased glomerular filtration rate (gfr). Renal dysfunction is also common in older cats … Read More

Ferguson D.C., Caffall Z. and Hoenig M. J Endocrinol, 2007. 194(2): p.267-73.   The obese cat is a model for the study of the progression toward type 2 diabetes. In this study, the impact of obesity on the hypothalamic-pituitary-thyroid axis … Read More

Barber L.G. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.755-73, vii.   The clinical presentation and biologic behavior of thyroid tumors vary widely among dogs, cats, and human beings. Although thyroid tumors in dogs are rare, they are … Read More

Feeney D.A. and Anderson K.L. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.799-821, viii.   The indications, techniques, and expectations for radionuclide diagnostic studies on canine and feline thyroid glands are presented. In addition, the considerations surrounding radioiodine … Read More

Peter V. Scrivani N.L.D., Richard B. Page, Hollis N. Erb, Vet Radiol Ultrasound, 2007. 48(4): p.383-387.   Our aim was to investigate thyroid:thyroid (T:T) ratio and visual inspection for assessing thyroid-lobe asymmetry in suspected hyperthyroid cats. Although thyroid2013salivary asymmetry is … Read More

Peterson M.E. and Ward C.R. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.633-45, v.   None of the studies to date have isolated a single dominant factor that could be incriminated in the development of hyperthyroidism in cats. … Read More

Radlinsky M.G. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.789-98, viii.   Thyroid surgery is indicated for malignant and benign neoplasms or hyperplasia of the thyroid glands. A ventral midline cervical approach allows for bilateral thyroid exploration. Care … Read More

Schenck P.A. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.693-708, vi.   Hyperthyroidism is the most common endocrine disorder of cats, and hypothyroidism is the most common endocrine disorder of dogs. Little is known regarding the effects of … Read More

Scott-Moncrieff J.C. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.709-22, vi.   Canine hypothyroidism may present with a wide range of clinical signs. The most common clinical signs are those of a decreased metabolic rate and dermatologic manifestations; … Read More

Shiel R.E. and Mooney C.T. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.671-91, vi.   Hyperthyroidism remains a common endocrine disorder of cats. Although relatively easy to diagnose in classically presenting cats, the increased frequency of testing cats … Read More

Syme H.M. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.723-43, vi.   In the simplest terms, hyperthyroidism is the clinical syndrome that results from an excess of thyroid hormones. This review considers the effects of hyperthyroidism on the … Read More

Trepanier L.A. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.775-88, vii.   Radioiodine is considered the treatment of choice for hyperthyroidism, but in some situations, methimazole therapy is preferred, such as in cats with preexisting renal insufficiency. Unfavorable … Read More

Ward C.R. Vet Clin North Am Small Anim Pract, 2007. 37(4): p.745-54, vii.   Thyroid storm is a syndrome described in human medicine to define a multisystemic disorder resulting from organ exposure to excessive levels of thyroid hormone. This form … Read More

Dye J.A. Conference Proceedings, (2007). American College of Veterinary Internal Medicine, Seattle:   Coincident with global introduction of BFRs into household consumer products nearly 30 years ago, hyperthyroidism in cats has increased considerably. The etiopathogenesis of feline hyperthyroidism remains unknown. … Read More

Morrison J. Conference Proceedings, (2007). American College of Veterinary Internal Medicine: p.643-644   Hyperthyroidism is one of the most common endocrine disorder in middle aged to older cats. Renal insufficiency may be masked by the presence of hyperthyroidism and subsequent … Read More

Mayer-Roenne B., Goldstein R.E. and Erb H.N. J Feline Med Surg, 2007. 9(2): p.124-32.   The prevalence of urinary tract infections (UTIs) in cats with hyperthyroidism (n=90), diabetes mellitus (DM) (n=57) and chronic kidney disease (CKD) (n=77) was evaluated retrospectively. … Read More

Niessen S.J., Voyce M.J., De Villiers L., et al. J Small Anim Pract, 2007. 48(3): p.165-8.   A nine-year-old, domestic shorthair cat was diagnosed with hyperthyroidism and treated with methimazole, which resulted in lethargy, inappetence and marked generalised lymphadenomegaly within … Read More

Szabo S.D. and Wells K.L. Journal of the American Veterinary Medical Association, 2007. 230(1): p.29-30. A 3-year-old neutered male domestic shorthair cat was referred for subtotal colectomy because of chronic constipation; the cat had had constipation since it was 6 … Read More

Boretti F.S., Sieber-Ruckstuhl N.S., Tschuor F., et al. Journal of Veterinary Internal Medicine, 2006. 20(6): p.1523-1524. During the last years alternative treatment of hyperthyroid cats using transdermal methimazole has increasingly been used. However, so far only one study evaluated treatment … Read More

Kirkby R., Scase T., Wakeling J.E., et al. Journal of Veterinary Internal Medicine, 2006. 20(6): p.1522. In human patients, a well-defined syndrome of sub-clinical hyperthyroidism exists where thyroid hormone concentrations are within the reference range but thyroid stimulating hormone concentration … Read More

Lien Y.H., Huang H.P. and Chang P.H. J Am Anim Hosp Assoc, 2006. 42(6): p.414-23. Iatrogenic hyperadrenocorticism is an extremely rare condition in cats. Twelve cats with a medical history of progressive skin lesions and long-term treatment with corticosteroids were … Read More

Naan E.C., Kirpensteijn J., Peeters M.E., et al. Journal of Veterinary Internal Medicine, 2006. 20(6): p.1523. The objective of this retrospective study was to describe the results of thyroidectomy in one hundred-and-one hyperthyroid cats, with emphasis on peri- and post-surgical … Read More

Paepe D., Smets P., Van Hoek I., et al. Journal of Veterinary Internal Medicine, 2006. 20(6): p.1522. Hyperthyroidism frequently affects older cats. Early diagnosis and treatment prevents development of deleterious complications. Thyroid gland palpation is an important aid for diagnosing … Read More

Wakeling J., Rob C., Elliott J., et al. Journal of Veterinary Internal Medicine, 2006. 20(6): p.1523.   Treatment of feline hyperthyroidism (HTH) is frequently associated with the unmasking of chronic renal failure (CRF). It is generally assumed that cats that … Read More

Daminet S. Conference Proceedings, (2006). World Congress, Prague: Feline hyperthyroidism and chronic renal failure (CRF) are common diseases In older cats. Further, renal function is profoundly influenced by thyroid statos tn several species. In cats, several studies have shown a … Read More

Dobias P. Conference Proceedings, (2006). World Congress WSAVA/FECAVA/CSAVA: p.124-126   Hyperthyroidism is one of the most commonly diagnosed problems in cats. The most frequently used conventional treatments involve the use of methimazole or Iodine 131. The following study is a … Read More

P. Y. Barthez, I. A. Schaafsma and Y. W. E. A. Pollak Vet Radiol Ultrasound, 2006. 47(5): p.503-506.   99mTc-pertechnetate is excreted in humans by the thyroid glands, gastric mucosa, salivary glands, choroid plexus, and sweat glands. Uptake attributed to … Read More

Behrend E.N. Vet Clin North Am Small Anim Pract, 2006. 36(5): p.1087-105, vii.   Drug therapy for the endocrine system is implemented to replace a hormone deficiency or to prevent or reduce the formation or effects of excess hormone. Treatment … Read More

Chalmers H.J., Scrivani P.V., Dykes N.L., et al. Vet Radiol Ultrasound, 2006. 47(5): p.507-9.   Because radioiodine (1-131) is excreted in urine and saliva, treated cats can accumulate I-131 on their coats from contacting soiled litter and grooming. This could … Read More

Ross S.J., Osborne C.A., Kirk C.A., et al. J Am Vet Med Assoc, 2006. 229(6): p.949-57.   Objective-To determine whether a renal diet modified in protein, phosphorus, sodium, and lipid content was superior to an adult maintenance diet in minimizing … Read More

Schaafsma I.A., Pollak Y.W. and Barthez P.Y. Am J Vet Res, 2006. 67(8): p.1362-6.   OBJECTIVES: To determine the effect of sedation and anesthesia on thyroid and salivary gland uptake of technetium Tc 99m pertechnetate ((99m)TcO(4)) in euthyroid cats. ANIMALS: … Read More

Buijtels J.J., Kurvers I.A., Galac S., et al. Tijdschr Diergeneeskd, 2006. 131(13): p.478-82.   Orally administered antithyroid drugs are frequently used to treat hyperthyroidism in cats; however, the non-cooperative behaviour of some cats may make it difficult to administer tablets. … Read More

Weiss D.J. J Feline Med Surg, 2006. 8(3): p.203-6.   A retrospective study of 128 feline bone marrow reports identified 13 cases of aplastic anemia. Clinical diagnoses included chronic renal failure (n=5), feline leukemia virus infection (n=2), hyperthyroidism treated with … Read More

Greco D.S. Vet Clin North Am Small Anim Pract, 2006. 36(3): p.549-56, vi.   Endocrine and metabolic disorders affecting puppies and kittens from birth until 6 months of age may manifest as clinical problems related to growth or to water … Read More

Sassnau R. Tierarztl Prax, 2006. 34: p.450-457.  

Wakeling J., Elliott J. and Syme H.S. Journal of Veterinary Internal Medicine, 2006. 20(3): p.726. Hyperthyroidism (HTH) in cats has strong parallels with toxic nodular goitre (TNG) in humans. A well-defined sub-clinical phase exists in TNG where thyroid hormone concentrations … Read More

Gilroy C.V., Horney B.S., Burton S.A., et al. Can J Vet Res, 2006. 70(2): p.137-42.   Hyperthyroidism can increase the renal excretion of magnesium and thus cause hypomagnesemia in various species. Anaerobically collected blood samples from 15 hyperthyroid and 40 … Read More

Naan E.C., Kirpensteijn J., Kooistra H.S., et al. Vet Surg, 2006. 35(3): p.287-93.   OBJECTIVE: To describe outcome after thyroidectomy in hyperthyroid cats, with emphasis on peri- and postsurgical complications and recurrence. STUDY DESIGN: Retrospective study. ANIMALS: One hundred and … Read More

Rayalam S., Eizenstat L.D., Hoenig M., et al. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore:    Hyperthyroidism is the most common endocrine disorder of elderly cats. However, its early diagnosis and studies of risk factors have been … Read More

Rayalam S., Eizenstat L.D., Davis R.R., et al. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore:    One out of every three hundred cats is now diagnosed with hyperthyroidism. A diagnostic tool that can sensitively detect changes in … Read More

Greco D.S. Clin Tech Small Anim Pract, 2006. 21(1): p.40-4.   Whereas hyperthyroidism is the most common endocrine disorder in the cat, hypothyroidism is the least common feline endocrine disorder. This is a the result of several factors including low … Read More

Page R.B., Scrivani P.V., Dykes N.L., et al. Vet Radiol Ultrasound, 2006. 47(2): p.206-11.   Our purpose was to determine the accuracy of increased thyroid activity for diagnosing hyperthyroidism in cats suspected of having that disease during pertechnetate scintigraphy using … Read More

Rayalam S., Eizenstat L.D., Hoenig M., et al. Domest Anim Endocrinol, 2006. 30(3): p.203-17.   The genes encoding the mature common glycoprotein alpha (CGA) and hormone-specific beta subunits of feline thyroid stimulating hormone (fTSH) were cloned and sequenced. The feline … Read More

Richard B. Page, Peter V. Scrivani, Nathan L. Dykes, et al. Vet Radiol Ultrasound, 2006. 47(2): p.206-211.   Our purpose was to determine the accuracy of increased thyroid activity for diagnosing hyperthyroidism in cats suspected of having that disease during … Read More

Birchard S.J. Clin Tech Small Anim Pract, 2006. 21(1): p.29-33.   Thyroidectomy in cats is most commonly indicated to treat hyperthyroidism because of adenomatous hyperplasia of the thyroid glands. Preoperative stabilization of the hyperthyroid cat with antithyroid drugs is preferred … Read More

Broome M.R. Clin Tech Small Anim Pract, 2006. 21(1): p.10-6.   Thyroid scintigraphy is a nuclear medicine procedure that produces a visual display of functional thyroid tissue based on the selective uptake of various radionuclides by thyroid tissue. Thyroid scintigraphy … Read More

Kemppainen R.J. and Birchfield J.R. Am J Vet Res, 2006. 67(2): p.259-65.   OBJECTIVE: To compare results obtained from assay of total thyroxine (T4) concentration in serum of dogs and cats by use of 4 methods. SAMPLE POPULATION: Serum samples … Read More

Langston C.E. and Reine N.J. Clin Tech Small Anim Pract, 2006. 21(1): p.17-21.   Hyperthyroidism and chronic renal failure (CRF) are both common diseases of older cats. Hyperthyroidism increases GFR by a variety of physiologic effects. Chronic renal failure can … Read More

Lecuyer M., Prini S., Dunn M.E., et al. Can Vet J, 2006. 47(2): p.131-5.   Thirteen cats, newly diagnosed with hyperthyroidism, were treated with a transdermal formulation of methimazole at a dose of 5 mg (0.1 mL) (concentration of 50 … Read More

Milner R.J., Channell C.D., Levy J.K., et al. J Am Vet Med Assoc, 2006. 228(4): p.559-63.   OBJECTIVE: To compare survival times for cats with hyperthyroidism treated with iodine 131, methimazole, or both and identify factors associated with survival time. … Read More

Peterson M.E. Clin Tech Small Anim Pract, 2006. 21(1): p.34-9.   Radioactive iodine provides a simple, effective, and safe treatment for cats with hyperthyroidism and is regarded by most authorities to be the treatment of choice. It is a particularly … Read More

Peterson M.E. Clin Tech Small Anim Pract, 2006. 21(1): p.2-9.   The diagnosis of hyperthyroidism, one of the most common disorders affecting elderly cats, is usually straightforward and considered routine by most practitioners. Nowadays, however, most cats suffering from hyperthyroidism … Read More

Trepanier L.A. Clin Tech Small Anim Pract, 2006. 21(1): p.22-8.   Radioiodine is considered the treatment of choice for hyperthyroidism, but in some situations, methimazole therapy is preferred, such as in cats with pre-existing renal insufficiency. Methimazole blocks thyroid hormone … Read More

Ward C.R. Conference Proceedings, (2006). American College of Veterinary Internal Medicine, Louisville: p.456-458   Thyroid storm is a syndrome described in human medicine to define a multi systemic disorder resulting from organ exposure to excessive levels of thyroid hormone.  This … Read More

Weichselbaum R.C., Feeney D.A. and Jessen C.R. Vet Radiol Ultrasound, 2005. 46(6): p.506-13.   Ninety-one spontaneously hyperthyroid cats were studied by two-dimensional and M-mode echocardiography with in a week before and 2-3 months following oral radioiodine administration. A statistical search … Read More

Todd D. Henrikson, Laura J. Armbrust, James J. Hoskinson, et al. Veterinary Radiology & Ultrasound, 2005. 46(6): p.521-523.   Thyroid to salivary (TS) ratio is the most commonly used scintigraphic parameter for differentiating euthyroid and hyperthyroid cats. Studies to determine … Read More

Sander D.M., Wolfsheimer K., Gallaher W.R., et al. Microsc Res Tech, 2005. 68(3-4): p.235-8.   The thyroid gland is afflicted in several endocrine, autoimmune, and malignant diseases. Previous studies detected immunoreactivity against proteins of a human intracisternal A-type retroviral particle … Read More

Henrikson T.D., Armbrust L.J., Hoskinson J.J., et al. Vet Radiol Ultrasound, 2005. 46(6): p.521-3.   Thyroid to salivary (TS) ratio is the most commonly used scintigraphic parameter for differentiating euthyroid and hyperthyroid cats. Studies to determine the normal TS ratio … Read More

Connolly D.J., Guitian J., Boswood A., et al. J Feline Med Surg, 2005. 7(5): p.289-300.   A raised concentration of serum cardiac troponin I (cTnI) is a sensitive marker of cardiac myocyte injury in the cat and assays developed for … Read More

Brennan S.F. and Jones B.R. European Journal of Companion Animal Practice, 2005. 15(2): p.169-172.   This paper discusses the clinical signs, diagnosis and treatment of hyperthyroidism. now recognized as the most common endocrine disease of the cat. Although the aetiology … Read More

Ward C.R., Achenbach S.E., Peterson M.E., et al. Am J Vet Res, 2005. 66(9): p.1478-82.   OBJECTIVE: To identify within guanosine triphosphate-binding proteins (G proteins) the subset of inhibitory G proteins (G) that have decreased expression in adenomatous thyroid glands … Read More

Lass P. and Kaniuka S. Hell J Nucl Med, 2005. 8(3): p.145-8.   This paper overviews the incidence, aetiology, clinical signs and complications of hyperthyroidism in cats as well as the contribution of nuclear medicine in the diagnosis and management … Read More

Garosi L., Mcconnell J.F., Platt S.R., et al. Journal of Veterinary Internal Medicine, 2005. 19(5): p.725-731.   Medical records of 33 dogs presented for acute onset, nonprogressive, intracranial dysfunction that had a magnetic resonance imaging diagnosis of brain infarction were … Read More

Riesen S.C. and Lombard C.W. J Am Vet Med Assoc, 2005. 227(4): p.556-8.

Romatowski J. J Am Vet Med Assoc, 2005. 227(1): p.32. I read with initial astonishment Nykamp et al’s recent report (JAVMA, May 15, 2005, pp 1671–1675) of a 30.3% incidence of posttreatment hypothyroidism among hyperthyroid cats treated with iodine 131 … Read More

Bromel C., Pollard R.E., Kass P.H., et al. J Vet Intern Med, 2005. 19(4): p.499-506.   Ultrasound evaluation of the thyroid gland was performed in healthy, hypothyroid, and euthyroid Golden Retriever dogs with nonthyroidal illness (NTI) to determine the diagnostic … Read More

Ward C.R., Dise D.G., Russell K.N., et al. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore: The pathogenesis of feline hyperthyroidism is not understood at the cellular or molecular level. Previous studies from our laboratory have identified a … Read More

Nykamp S.G., Dykes N.L., Zarfoss M.K., et al. J Am Vet Med Assoc, 2005. 226(10): p.1671-5.   OBJECTIVE: To assess whether the risk of development of hypothyroidism after treatment with iodine 131 (131I) was associated with the pattern of sodium … Read More

Anthony J. Fischetti, Wm Tod Drost, Stephen P. Dibartola, et al. Veterinary Radiology & Ultrasound, 2005. 46(3): p.267-272.   Nineteen cats with abnormally high serum T4 concentrations underwent thyroid scintigraphy using technetium-99m pertechnetate (99mTcO4) before and after 36±6 days of … Read More

Meeking S.A. Vet Clin North Am Small Anim Pract, 2005. 35(3): p.635-53.   Thyroid disorders are common in older pets. They often present a diagnostic challenge, and reaching a definitive diagnosis can be difficult or impossible in some cases. It … Read More

Worth A.J., Zuber R.M. and Hocking M. Aust Vet J, 2005. 83(4): p.208-14.   OBJECTIVE: To assess the efficacy of radioactive iodine treatment (131I) for canine thyroid carcinoma, as both the sole therapeutic modality and as an adjunct to surgery. … Read More

Mellanby R.J., Jeffery N.D., Gopal M.S., et al. J Feline Med Surg, 2005. 7(2): p.135-9.   An 18-month-old female neutered domestic short hair cat was examined because of marked polydipsia and stunted growth following head trauma when it was 8 … Read More

Ward C.R., Achenbach S.E., Holt D., et al. Thyroid, 2005. 15(2): p.114-20.   Feline hyperthyroidism is a common, spontaneous disease in older cats that is similar clinically and histopathologically to human toxic multinodular goiter (TNG). In this study, the functional … Read More

Olczak J., Jones B.R., Pfeiffer D.U., et al. N Z Vet J, 2005. 53(1): p.53-8.   AIM: To search for putative risk factors for feline hyperthyroidism in New Zealand, using a case-control study. METHODS: A questionnaire-based case-control study involving the … Read More

Declercq J. and Bhatti S. Vet Dermatol, 2005. 16(1): p.74-8.   Calcinosis of multiple paws is described in two cats. A metastatic pathogenesis was supported by the laboratory findings of hyperphosphataemia and a calcium x phosphorus solubility product > 7 … Read More

Wakeling J., Melian C., A. F., et al. Conference Proceedings, (2005). Proceedings of the 15th ECVIM-CA Congress: p.2005   There is much anecdotal evidence that the incidence of feline hyperthyroidism (HTH) varies hugely between different geographical locations. If this were … Read More

Steiner J.M., Peterson M.A., Ruaux C.G., et al. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore: Cats with hyperthyroidism commonly show vomiting and/or diarrhea, which are believed to be clinical signs due to direct effects of thyroid hormones … Read More

Jepson R.E., Elliott J. and Syme H.M. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore:   A proportion of hyperthyroid cats that have normal blood pressure at diagnosis become hypertensive following treatment. The aim of this study was … Read More

Jacobson J.D. Vet Med, 2005. 100(7): p.518-526.   What agents and monitoring devices might be better in these patients? This anesthesiologist tells you how to handle common situations, such as: “Based on the results of physical examination and routine screening … Read More

Gunn-Moore D. Vet Clin North Am Small Anim Pract, 2005. 35(1): p.171-210, vii.   Feline endocrinopathies (excluding diabetes mellitus) include hyperthyroidism, hypothyroidism, acromegaly, hyposomatotropism, diabetes insipidus, hyperadrenocorticism, primary sex hormone-secreting adrenal tumors, primary hyperaldosteronism, pheochromocytoma, hypoadrenocorticism, hyperparathyroidism, and hypoparathyroidism. Each … Read More

Ferguson D.C. Conference Proceedings, (2005). American College of Veterinary Internal Medicine, Baltimore: Great strides have been made in the recognition of feline hyperthyroidism since its first description as a clinical entity over 25 years ago. However, there remain significant issues … Read More

Bruyette D. Vet Med, 2004. 99(11): p.956-962.   Not all hyperthyroid cats exhibit clinical signs, and concurrent illness may skew the laboratory assessment of thyroid function. Here’s the latest research on what tests to perform to establish a diagnosis. In … Read More

Edinboro C.H., Scott-Moncrieff J.C. and Glickman L.T. Thyroid, 2004. 14: p.722.   The prevalence of feline hyperthyroidism has increased dramatically since it was first reported in the late 1970s. It is now recognized as the most common endocrine disorder of … Read More

Sartor L.L., Trepanier L.A., Kroll M.M., et al. J Vet Intern Med, 2004. 18(5): p.651-5.   The objective of this study was to determine whether transdermal methimazole was as safe and effective as oral methimazole for the control of hyperthyroidism … Read More

Edinboro C.H., Scott-Moncrieff J.C. and Glickman L.T. Thyroid, 2004. 14: p.759.   Cats now live in approximately 34% of American households. With an average of two cats per home, this represents about 73 million cats that share the household environment … Read More

Smith J.R. and Elwood C.M. J Small Anim Pract, 2004. 45(8): p.405-9.   Traumatic hypopituitarism was diagnosed in an 11-month-old male neutered cat. The presenting complaints were polydipsia, polyuria and lethargy of three months’ duration. Craniocerebral trauma, as a result … Read More

Miles K.G., Simpson S.A., Zimmerman R.B., et al. Conference Proceedings, (2004). American College of Veterinary Radiology, Montreal:   INTRODUCTION/PURPOSE: Radioactive iodine (I-131) therapy represents the current gold standard treatment option for feline hyperthyroidism. At present, release criteria for treated cats … Read More

Blackwood L. Vet J., 2004. 168(1): p.50-59.   The use of human adenovirus (Ad) vectors for transcriptionally targeted thyroid gene therapy was investigated, aiming to develop a novel therapy for feline hyperthyroidism. Ad5 (El, E3 deleted) vectors were constructed in … Read More

Court M.H. J Am Vet Med Assoc, 2004. 224(10): p.1581-2; author reply 1582-3. I read with great interest the article by Edinboro et al (JAVMA, March 15, 2004, pp 879–886) describing an epidemiologic investigation of feline hyperthyroidism. The main finding … Read More

White H.L., Freeman L.M., Mahony O., et al. Am J Vet Res, 2004. 65(5): p.586-91.   OBJECTIVE: To compare effects of short-term administration of a soy diet with those of a soy-free diet on serum thyroid hormone concentrations in healthy … Read More

Thompson J. Can Vet J, 2004. 45(5): p.427-9.   Hyperthyroidism and chronic renal disease occur commonly in geriatric cats, often in association with potentially life-threatening primary or secondary hypertension. Early treatment of hypertension minimizes damage to vital organs. This case … Read More

Moore K. Conference Proceedings, (2004). BSAVA Congress 2004: p.521   Hyperthyroidism can be difficult to diagnose in cats with renal disease since the total thyroxine (tT4) concentration is frequently within the laboratory reference range. This study investigated whether the measurement … Read More

Edinboro C.H., Scott-Moncrieff J.C., Janovitz E., et al. J Am Vet Med Assoc, 2004. 224(6): p.879-86.   OBJECTIVE: To determine whether the increasing prevalence of feline hyperthyroidism is the result of aging of the cat population and whether consumption of … Read More

Panciera D. Vet Med, 2004. 99(2): p.154-168.   Once a diagnosis of neoplasia of the thyroid gland is suspected or confirmed, a variety of treatments are available for dogs and cats. In this article, we first review the available therapeutic … Read More

Page R.B. American College of Veterinary Radiology, Scientific Proceedings, 2004. p.32. The purpose o f this study was to determine the accuracy of detecting an elevated thyroid: salivary ratio (T: S) during subcutaneous thyroid scintigraphy (SQTS) for diagnosing hyperthyroidism in … Read More

Drost W.T., Mattoon J.S., Samii V.F., et al. Vet Radiol Ultrasound, 2004. 45(2): p.112-6.   We studied the computed tomographic (CT) appearance and determined Hounsfield units (HU) for normal thyroid tissue in eight cats. Helical CT images (2 mm collimation) … Read More

Schenck P.A. Supplement to Compendium on Continuing Education for the Practicing Vet., 2004. 26(2(A)): p.22-23.   Hyperthyroidism was first reported in cats in 1979. Since that time, it has become the most common endocrinopathy in cats. Morphology of affected thyroid … Read More

Sansom J., Rogers K. and Wood J.L. Am J Vet Res, 2004. 65(2): p.245-52.   OBJECTIVE: To determine whether there was an association between hypertensive retinopathy and high systolic, diastolic, and mean arterial blood pressures in cats. ANIMALS: 181 cats. … Read More

Crowe A. Can Vet J, 2004. 45(2): p.168, 170. An 18-month-old, 2 kg, intact female domestic shorthair was presented for a 2-day history of decreased appetite and lethargy. The owner had also noted that there was a decrease in the … Read More

De Lange M.S., Galac S., Trip M.R., et al. J Vet Intern Med, 2004. 18(2): p.152-5.   Measurement of the urinary corticoid : creatinine (C : C) ratio provides an assessment of cortisol secretion over a period of time. Therefore, … Read More

Bruyette D. Vet Med, 2004. 99(11): p.951-954.   Since it was first documented in 1979, hyperthyroidism has become increasingly more common in cats. It is now the most commonly diagnosed endocrinopathy in cats. This may be a true increase in … Read More

Bruyette D. Vet Med, 2004. 99(11): p.964-972.   You have numerous choices for treating hyperthyroid cats. Which therapy you choose depends on such factors as the cat’s health, the expense the owner is willing to bear, your experience, and the … Read More

Mallery K.F., Pollard R.E., Nelson R.W., et al. J Am Vet Med Assoc, 2003. 223(11): p.1602-7.   OBJECTIVE: To determine efficacy and safety of percutaneous radiofrequency heat ablation for treatment of hyperthyroidism in cats. DESIGN: Prospective study. ANIMALS: 9 cats. … Read More

Feeney D.A., Jessen C.R., Weichselbaum R.C., et al. Am J Vet Res, 2003. 64(10): p.1242-1247.   OBJECTIVE: To determine the relationship between surface emission rate of gamma radiation and urine concentration of I131 (urine radioactivity) during the period 7 to … Read More

Slater L., Neiger R., Haller M., et al. Conference Proceedings, (2003). American College of Veterinary Internal Medicine: p.742   It is generally believed that there is a decline in renal function following treatment of hyperthyroidism in cats, but no long-term … Read More

Phillips D.E., Radlinsky M.G., Fischer J.R., et al. J Am Anim Hosp Assoc, 2003. 39(4): p.349-54.   Reports of cystic thyroid and parathyroid masses in cats are uncommon. Herein, the authors describe a series of four cats with cystic ventral … Read More

Syme H.M. and Elliott J. Conference Proceedings, (2003). American College of Veterinary Internal Medicine:   Proteinuria is related to survival time in humans with renal failure. The aim of this study was to investigate the relationship of proteinuria to survival … Read More

Peterson M.E., Demarco C.L. and Sheldon K.M. Conference Proceedings, (2003). American College of Veterinary Internal Medicine: p.396   Endocrine testing of dogs and cats is commonplace in clinical practice. Feline hyperthyroidism and canine hypothyroidism comprise the most frequently encountered endocrinopathies … Read More

Sartor L.L., Trepanier L.A., Kroll M., et al. Conference Proceedings, (2003). American College of Veterinary Internal Medicine: p.393   Methimazole (Tapazole) is the drug of choice for the medical management of feline hyperthyroidism in the United States. Recently, custom veterinary … Read More

Weichselbaum R.C., Feeney D.A. and Jessen C.R. Am J Vet Res, 2003. 64(4): p.425-7.   OBJECTIVE: To determine relationships between commonly measured pretreatment variables and duration of isolation for unrestricted dismissal after oral administration of iodine 131 (131I) for treatment … Read More

Trepanier L.A., Hoffman S.B., Kroll M., et al. J Am Vet Med Assoc, 2003. 222(7): p.954-8.   OBJECTIVE: To determine whether once daily administration of methimazole was as effective and safe as twice daily administration in cats with hyperthyroidism. DESIGN: … Read More

Hoffmann G., Marks S.L., Taboada J., et al. J Feline Med Surg, 2003. 5(2): p.77-82.   The objectives of this study were to assess serum thyroxine concentrations and clinical response in hyperthyroid cats to treatment with transdermal methimazole, and to … Read More

Syme H.M. and Elliott J. J Vet Intern Med, 2003. 17: p.754-755. Hyperthyroidism has been reported as an important cause of hypertension in the cat. However systematic studies of blood pressure in hyperthyroid cats have not been reported and, in … Read More

Stepien R.L., Rapoport G.S., Henik R.A., et al. J Vet Intern Med, 2003. 17: p.754. Elevated blood pressure (BP) is reported to occur in the majorily of cats with hyperthyroidism but measurement method and patient temperament or level of anxiety(“white coat effect”) may alter … Read More

Smith S.A., Tobias A.H., Jacob K.A., et al. J Vet Intern Med, 2003. 17(1): p.73-83.   Records of 127 cats with arterial thromboembolism (ATE) were reviewed. Abyssinian, Birman, Ragdoll, and male cats were overrepresented. Tachypnea (91%), hypothermia (66%), and absent … Read More

Chetboul V., Lefebvre H.P., Pinhas C., et al. J Vet Intern Med, 2003. 17(1): p.89-95.   Systemic hypertension was diagnosed in 58 of 188 untreated cats referred for evaluation of suspected hypertension-associated ocular, neurologic. cardiorespiratory, and urinary disease, or diseases … Read More

Gordon J.M., Ehrhart E.J., Sisson D.D., et al. J Am Anim Hosp Assoc, 2003. 39(1): p.67-71.   An 8-month-old, male domestic shorthaired cat presented for chronic weight loss, intermittent dyspnea, chronic diarrhea, hyperactivity, and weakness. The cat had a palpable … Read More

Marsolais M.E., Mott J. and Berry C.R. Conference Proceedings, (2003). American College of Veterinary Internal Medicine: p.393 Diagnosis of hyperthyroidism is traditionally made by demonstrating elevations in the serum thyroxine (T4) level; however, fluctuations in T4 levels and the possibility … Read More

Puille M., Knietsch M., Spillmann T., et al. Nuklearmedizin, 2002. 41(6): p.245-51.   AIM: Establishment of radioiodine treatment of feline hyperthyroidism in veterinary routine in accordance with German radiation protection regulations. PATIENTS AND METHODS: 35 cats with proven hyperthyroidism were … Read More

Chun R., Garrett L.D., Sargeant J., et al. Vet Radiol Ultrasound, 2002. 43(6): p.587-91.   The objective of this retrospective study was to evaluate hyperthyroid cats for pretreatment factors that would predict response to radioiodine therapy. Hyperthyroidism was diagnosed in … Read More

Malik R. and Charlton V. J Feline Med Surg, 2002. 4(3): p.127-8. Unlike most clinical academics, I have the opportunity of seeing a reasonable number of first opinion cases, as well as feline referrals . This gives me the opportunity … Read More

Mooney C.T. J Feline Med Surg, 2002. 4(3): p.167-9.   Hyperthyroidism is recognised not only as the commonest endocrine disease of domestic cats but as one of the most frequently diagnosed disorders in small animal practice. Prior to its first … Read More

Norsworthy G.D., Adams V.J., Mcelhaney M.R., et al. J Feline Med Surg, 2002. 4(3): p.145-51.   Client-owned cats underwent surgery to remove palpable cervical masses in cats with normal total T4 values and no clinical signs of hyperthyroidism, renal disease, … Read More

Norsworthy G.D., Adams V.J., Mcelhaney M.R., et al. J Feline Med Surg, 2002. 4(3): p.139-43.   In 155 cats, both with and without clinical signs of hyperthyroidism, total thyroxine (TT4) concentrations were compared to a sensitive, semi-quantitative thyroid palpation technique. … Read More

Otero T., Archer J., Billings H., et al. Conference Proceedings, (2002). Proceedings of the European College of Veterinary Internal Medicine—Companion Animals Congress: p.173   Feline hyperthyroidism can be difficult to diagnose. Sensitive TSH assays are used to diagnose this condition … Read More

Daniel G.B., Sharp D.S., Nieckarz J.A., et al. Vet Radiol Ultrasound, 2002. 43(4): p.374-82.   Quantitative thyroid scintigraphy using pertechnetate was performed in 43 cats with various T4 concentrations and compared to eight normal control cats. Quantitative parameters included percentage … Read More

Lurye J.C., Behrend E.N. and Kemppainen R.J. J Am Vet Med Assoc, 2002. 221(2): p.243-9.   OBJECTIVE: To compare serum total thyroxine (T4) concentrations obtained with an in-house ELISA and a validated radioimmunoassay (RIA). DESIGN: Laboratory trial. SAMPLE POPULATION: 50 … Read More

Padgett S. Vet Clin North Am Small Anim Pract, 2002. 32(4): p.851-9, vi.   Hyperthyroidism is the most commonly diagnosed endocrine disease in cats. Surgery is a widely available curative therapy for hyperthyroid cats. Because of the multiple metabolic changes … Read More

Peeters M.E., Timmermans-Sprang E.P. and Mol J.A. Thyroid, 2002. 12(7): p.571-5.   The etiopathogenesis of feline thyrotoxicosis is unknown. The transmembrane part (gene codons 480-640) of the thyrotropin receptor (TSHR) gene of hyperthyroid cats has already been investigated for the … Read More

Hoffman S.B., Yoder A.R. and Trepanier L.A. J Vet Pharmacol Ther, 2002. 25(3): p.189-93.   The antithyroid drug methimazole is widely used for the medical management of feline hyperthyroidism. Recently, custom veterinary pharmacies have offered methimazole in a transdermal gel … Read More

Ranz D., Tetrick M., Opitz B., et al. J Nutr, 2002. 132(6 Suppl 2): p.1751S-3S. Feline hyperthyroidism is the most common endocrine disorder of middle-aged to old cats in the United States. In Germany, the latest investigations have shown increasing … Read More

Syme H.M., Barber P.J., Markwell P.J., et al. J Am Vet Med Assoc, 2002. 220(12): p.1799-804.   OBJECTIVE: To determine prevalence of systolic hypertension and associated risk factors in cats with chronic renal failure evaluated in first-opinion practice. DESIGN: Prospective … Read More

Miyamoto T., Ikuko M., Kenji K., et al. J Jap Vet Med Assoc, 2002. 55: p.289-292.

Buffington C.A. J Am Vet Med Assoc, 2002. 220(7): p.994-1002.   Owners surrender millions of cats to animal shelters each year for euthanasia. Inappropriate elimination, most commonly associated with urologic signs, was the must common reason given for abandoning the cat. … Read More

Blackwood L. and Argyle D.J. J Small Anim Pract, 2002. 43(2): p.58-66.   Feline hyperthyroidism is the most common endocrine disorder of the elderly cat. Traditionally, the disease is treated by surgical thyroidectomy, medical management with antithyroid drugs or radiation … Read More

Court M.H. and Freeman L.M. Am J Vet Res, 2002. 63(2): p.181-5.   OBJECTIVE: To determine the absolute and relative soy isoflavone content in commercial cat foods. SAMPLE POPULATION: 14 dry, 6 semimoist, and 22 moist commercial cat foods. PROCEDURE: … Read More

Kaplan E. Can Vet J, 2002. 43(2): p.117-9.   A cat was presented for anorexia and vomiting. Hyperthyroidism and primary hyperparathyroidism were diagnosed. A thyroid adenoma and parathyroid adenoma, respectively, were responsible for these conditions. Unilateral thyroidectomy and parathyroidectomy successfully … Read More

Nguyen L.Q., Arseven O.K., Gerber H., et al. Endocrinology, 2002. 143(2): p.395-402.   Cats are the only nonhuman mammalian species with a high incidence of hyperthyroidism, and a better understanding of the pathogenesis of feline hyperthyroidism is of clinical relevance … Read More

Reese S.L., Kurzke E., Hermanns W., et al. Tierarztl Prax Ausg K Kleintiere Heimtiere, 2002. 30(K): p.274-281.  

Ferguson D. Conference Proceedings, (2002). ACVIM: p.511-513 It has been said that If a person lives long enough, eventually a nodular goiter will develop. Adenomatous hyperplasia or nodular goiter in the cat Is similar to nodular goiter in man with … Read More

Kooistra H.S., De Lange M., Trip M., et al. Conference Proceedings, (2002). ECVIM-CA: p.637   Elevated urinary corticoid/creatinine (C/C) ratios in cats with signs and symptoms compatible with hyperadrenocorticism have been reported to be indicative of hyperadrenocortism.  However, in addition … Read More

Syme H. Conference Proceedings, (2002). 12th ECVIM-CA/ESVIM Congress 2002:   Diagnosis of hyperthyroidism in cats with chronic renal failure (CRF) can be problematic, as many cats will have normal total thyroxine (TT4) due to sick euthyroid syndrome. Free thyroxine (ff4) … Read More

Utiger R.D. Clinical Thyroidology, 2002. 14(1): p.6. Hyperthyroidism is far more common in cats than in other animals. The usual causes are a toxic    uninodular or multinodular goiter, but a few cats seem to have a diffuse goiter, raising … Read More

Elwood C.M., White R.N., Freeman K., et al. J Feline Med Surg, 2001. 3(4): p.247-252.   A 14-year-old domestic short-hair cat presented with a history of intermittent malaise and increased drinking. A diagnosis of hyperthyroidism and cholelithiasis was made by … Read More

Mooney C.T. Vet Clin North Am Small Anim Pract, 2001. 31(5): p.963-83, viii.   Today, hyperthyroid cats are less symptomatic than those 10 or 15 years ago, and early diagnosis impacts the range and severity of the routine clinicopathological abnormalities … Read More

Nieckarz J.A. and Daniel G.B. Vet Radiol Ultrasound, 2001. 42(5): p.448-57.   Many hyperthyroid cats referred for thyroid imaging and 131I therapy are concurrently or recently receiving antithyroid medications. The effect of the antithyroid drug, methimazole, on thyroid uptake of … Read More

Tobias S. and Labato M.A. Vet Med, 2001. 96: p.719-726. Congenital primary hypothyroidism causing disproportionate dwarfism is seldom diagnosed and rarely reported to occur in cats. The clinical signs of congenital hypothyroidism can range from severe to mild depending on … Read More

Bruyette D.S. Vet Clin North Am Small Anim Pract, 2001. 31(5): p.1063-81, ix.   This article highlights the advances in feline endocrinology, excluding diabetes mellitus and hyperadrenocorticism, which have recently been reviewed elsewhere. The goal will be to provide clinically … Read More

Hofmeister E., Kippenes H., Mealey K.L., et al. J Am Vet Med Assoc, 2001. 219(2): p.190-3.   A 9-year-old cat with hyperthyroidism was referred for radioactive iodine treatment. The cat also had a ventral cervical mass that the owners reported … Read More

Foster D.J., Thoday K.L., Arthur J.R., et al. Am J Vet Res, 2001. 62(6): p.934-7.   OBJECTIVE: To assess selenium (Se) status of cats in 4 regions of the world and to compare results for Se status with reported incidence … Read More

Tomsa K., Hardegger R., Glaus T., et al. Conference Proceedings, (2001). American College of Veterinary Internal Medicine:   99mTc-PERTECHNETATE SCINTIGRAPHY IN HYPERTHYROID CA TS WITH NORMAL SERUM THYROXINE CONCENTRATIONS. K. Tomsa1, R. Hardegger2, T. Glaus1, C. Reusch1. 1Clinic for Small … Read More

Gnudi G., Bertoni G., Luppi A., et al. Vet Radiol Ultrasound, 2001. 42(3): p.250-3.   A 5 month-old, male, domestic short hair cat was presented with inappetence and vomiting. it was depressed and reluctant to move. The cat had difficulties … Read More

Goldstein R.E., Long C., Swift N.C., et al. J Am Vet Med Assoc, 2001. 218(8): p.1298-302. Hyperthyroidism is a commonly diagnosed endocrine disease in cats. Current treatment options include long-term use of antithyroid medications, thyroidectomy, and administration of radioactive iodine … Read More

Wells A.L., Long C.D., Hornof W.J., et al. J Am Vet Med Assoc, 2001. 218(8): p.1293-7.   OBJECTIVE: To determine the efficacy and safety of percutaneous ethanol injection (PEI) for the treatment of hyperthyroidism caused by bilateral hyperplastic thyroid nodules … Read More

Elliott J., Barber P.J., Syme H.M., et al. J Small Anim Pract, 2001. 42(3): p.122-9.   Systolic hypertension was diagnosed in 30 cats. At diagnosis, 16 of those were found to be in chronic renal failure only, while five were … Read More

Greco D.S. Vet Clin North Am Small Anim Pract, 2001. 31(2): p.401-9, viii.   Endocrine and metabolic disorders affecting puppies and kittens from birth until 6 months of age may manifest as clinical problems related to growth, water metabolism (polydipsia … Read More

Panciera D.L. J Vet Intern Med, 2001. 15(2): p.86-8. Regulation of circulating thyroid hormones is a complex process that involves the hypothalamus, pituitary gland, thyroid gland, plasma transport proteins, and cellular uptake and metabolism of thyroid hormones. The hypothalamus produces … Read More

Tomsa K., Glaus T.M., Kacl G.M., et al. J Vet Intern Med, 2001. 15(2): p.89-93.   Basal serum thyroxine (T4) concentration and the thyrotropin-releasing hormone (TRH) stimulation test were used to assess thyroid function in 36 critically ill cats examined … Read More

Peterson M.E., Melian C. and Nichols R. J Am Vet Med Assoc, 2001. 218(4): p.529-36.   OBJECTIVE: To determine the usefulness of measuring serum free thyroxine (T4) concentration as a diagnostic test for hyperthyroidism in cats, and to determine the … Read More

Slater M.R., Geller S. and Rogers K. J Vet Intern Med, 2001. 15(1): p.47-51.   Two hundred thirty-one cats treated with radioactive iodine at the Texas Veterinary Medical Teaching Hospital were followed for a median of 25 months by means … Read More

Syme H.M. and Elliott J. Conference Proceedings, (2001). American College of Veterinary Internal Medicine, Denver:   Many cats are diagnosed with renal failure (RF) following treatment for hyperthyroidism.It is uncertain whether this is due to the deleterious effects of  hyperthyroidism … Read More

Ward C.E., Achenbach S.E. and Peterson M.E. Conference Proceedings, (2001). American College of Veterinary Internal Medicine:   Feline hyperthyroidism is a common endocrinopathy in cats that resembles toxic nodular goiter (TNG) in humans.  Abnormalities of the TSH receptor-G protein-mediated signal … Read More

Maggio F., Defrancesco T.C., Atkins C.E., et al. Journal of the American Veterinary Medical Association, 2000. 217(5): p.695-702.   OBJECTIVE: To characterize clinical and clinicopathologic findings, response to treatment, and causes of systemic hypertension in cats with hypertensive retinopathy. DESIGN: … Read More

Martin K.M., Rossing M.A., Ryland L.M., et al. J Am Vet Med Assoc, 2000. 217(6): p.853-6.   OBJECTIVE: To identify dietary and environmental risk factors for hyperthyroidism in cats. DESIGN: Case-control study. ANIMALS: 100 cats with hyperthyroidism and 163 control … Read More

Patnaik A.K., Peterson M.E. and Hidgon A. J Feline Med Surg, 2000. 2(3): p.143-6.   Ectopic thyroid tissue was identified at the base of the tongue in a 9-year-old, euthyroid, domestic shorthair cat. The lingual submucosa and the muscles were … Read More

Hammer K.B., Holt D.E. and Ward C.R. Am J Vet Res, 2000. 61(8): p.874-9.   OBJECTIVE: To determine whether expression of G proteins (G(i) and G(s)) is altered in thyroid gland adenomas obtained from hyperthyroid cats. SAMPLE POPULATION: Adenomatous thyroid … Read More

Olczak J. Conference Proceedings, (2000). Proceedings of the 9th Symposium of hte International Society for Veterinary Epidemiology and Economics, Breckenridge, CO:   A questionnaire-based case-control study involving 375 New Zealand cats was conducted to examine associations between putative risk factors … Read More

Bucknell D.G. Aust Vet J, 2000. 78(7): p.462-5.   OBJECTIVE: To determine the spectrum of clinical presentations of hyperthyroidism in cats and response to carbimazole therapy by analysis of historical, clinical and laboratory data. DESIGN: A prospective clinical study involving … Read More

Becker T.J., Graves T.K., Kruger J.M., et al. J Am Anim Hosp Assoc, 2000. 36(3): p.215-23.   The purpose of this study was to investigate the effects of methimazole on renal function in cats with hyperthyroidism. Twelve cats with naturally … Read More

Elliott J., Rawlings J.M., Markwell P.J., et al. J Small Anim Pract, 2000. 41(6): p.235-42.   Fifty cats with naturally occurring stable chronic renal failure (CRF) were entered into a prospective study on the effect of feeding a veterinary diet … Read More

Ward C.R., Achenbach S.E., Peterson M.E., et al. Journal of Veterinary Internal Medicine, 2000. 14: p.342.   Feline hyperthyroidism is a common, spontaneously occurring endocrine disease seen in middle-older aged cats.  It is similar both histologically and functionally to human … Read More

Foster D.J., Thoday K.L. and Beckett G.J. J Mol Endocrinol, 2000. 24(1): p.119-26.   We have investigated thyroid hormone deiodination in the liver, kidney and thyroid of the domestic cat. Affinity labelling with (125)I-bromoacetyl reverse T(3) (125)(I-BrAc-rT(3) demonstrated that liver … Read More

Van Der Woerdt A. and Peterson M.E. J Vet Intern Med, 2000. 14(2): p.202-3.   The purpose of this study was to investigate the occurrence of ocular abnormalities in hyperthyroid cats. One hundred hyperthyroid cats and 30 clinically normal, geriatric … Read More

Foster D.J. and Thoday K.L. Res Vet Sci, 2000. 68(1): p.89-94.   The concentration of serum alkaline phosphatase (SALP) is commonly elevated in hyperthyroid cats. Agarose gel electrophoresis, in tris -barbital-sodium barbital buffer, with and without the separation enhancer neuraminidase, … Read More

Swainson S.W., Nelson O.L., Niyo Y., et al. Vet Radiol Ultrasound, 2000. 41(1): p.41-3. Right lateral and dorsoventral thoracic radiographs were made at the time of initial presentation (Fig. 1). A well circumscribed soft tissue mass was identified within the … Read More

Christopher M.M. and O’neill S. Vet Clin Pathol, 2000. 29(1): p.22-28.   The objective of this study was to compare and investigate differences in glucose and lactate concentrations in sodium fluoride/potassium oxalate (NaF/Ox) plasma and serum in healthy cats and … Read More

Randolph J.F., Demarco J., Center S.A., et al. J Vet Intern Med, 2000. 14(1): p.56-9.   The effect of daily doses of 5-15 mg of methimazole on the platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT), and proteins … Read More

Chun R., Garrett L.D., Sherman A., et al. Conference Proceedings, (1999). American College of Veterinary Radiology, Chicago, IL:   Introduction Feline hyperthyroidism was first recognized in 1979 and is now the most frequently diagnosed endocrinopathy in cats. Many studies have … Read More

Gelatt-Nicholson K. and Neuwirth L. Conference Proceedings, (1999). American College of Veterinary Radiology, Chicago, IL:   Purpose: To compare T4 levels and thyroid scintigraphy in the evaluation of feline hyperthyroidism. Emphasis was placed on the scintigraphic results of cats with … Read More

Tognella C., Peter H.J., Wagner H., et al. J Endocrinol, 1999. 163: p.505-514.   Interactions between follicular epithelia cells and extracellular matrix (EM)/basal membrane (BM) are supposed to play an important role in development and maintenance of thyroid tissue architecture. … Read More

Reusch C.E. and Tomsa K. J Am Vet Med Assoc, 1999. 215(9): p.1297-300.   OBJECTIVE: To determine the effect of hyperthyroidism on serum fructosamine concentration in cats. DESIGN: Cohort study. ANIMALS: 22 cats with overt hyperthyroidism. PROCEDURE: Hyperthyroidism was diagnosed … Read More

Graham P.A., Mooney C.T. and Murray M. Res Vet Sci, 1999. 67(2): p.171-5.   Serum fructosamine concentrations were measured in 35 healthy cats and in 30 hyperthyroid cats before and 30 days after curative radioiodine ((131)I) treatment. Hyperthyroid cats were … Read More

Walker M.C. Fel Prac, 1998. 26(5): p.10-12.   This case report describes the treatment of hyperthyroidism in a 8 1/2 year old female spayed Domestic Shorthair with intrathyroid injection of ethanol. The cat had been only partially responsive to I-131 … Read More

Flanders J.A. J Feline Med Surg, 1999. 1(3): p.127-34.   Since the first description of feline hyperthyroidism in 1978, numerous treatment options for hyperthyroidism have been reported. Surgical removal of enlarged, autonomously functioning thyroid glands is one of the most … Read More

Foster D.J. and Thoday K.L. J Small Anim Pract, 1999. 40(7): p.307-15.   A prospective study was carried out using a combination of propranolol and potassium iodate to assess whether there were beneficial effects in preparing hyperthyroid cats for surgical … Read More

Kass P.H., Peterson M.E., Levy J., et al. J Vet Intern Med, 1999. 13(4): p.323-9.   The pathologic changes associated with hyperthyroidism (adenomatous hyperplasia, adenoma of the thyroid gland) have been well characterized in cats, but the pathogenesis of these … Read More

Ward C.R. Conference Proceedings, (1998). American College of Veterinary Internal Medicine:   Hyperthyroidism is a common endocrinopathy in geriatric cats that resembles toxic nodular goiter in humans. It results from single or multiple hyperplastic thyroid nodules that retain the ability … Read More

Yu M.D., Peck G.E., Scott-Moncrieff J.C., et al. Drug Dev Ind Pharm, 1999. 25(5): p.565-70.   This investigation was designed to compare in vitro dissolution profiles from sodium iodide capsules with radioiodide thyroid uptake in hyperthyroid cats using sodium iodide … Read More

Behrend E.N. Compen Contin Educ Pract Vet., 1999. 21(3): p.235-244.   Hyperthyroidism is the most common endocrinopathy of cats. Antithyroid medications and radioiodine constitute the two main medical options. Methimazole and carbimazole are effective in most cats, but monitoring is … Read More

Merryman J.I., Buckles E.L., Bowers G., et al. Vet Pathol, 1999. 36(2): p.117-24.   Formalin-fixed, paraffin-embedded thyroid glands from 18 cats diagnosed with hyperthyroidism were evaluated immunohistochemically for overexpression of the products of oncogenes c-ras and bcl2 and the tumor … Read More

Ferguson D.C., Glawe P., Miller M., et al. Veterinary Forum, 1999. (August): p.50-57.

Chaitman J., Hess R., Senz R., et al. J Vet Intern Med, 1999. 13: p.242 (abstract). This study describes a population of cats with a histologic diagnosis of thyroid adenomatous hyperplasia (TAH) with normal serum thyroxine concentrations and the absence … Read More

Fox P.R., Peterson M.E. and Broussard J.D. J Am Anim Hosp Assoc, 1999. 35(1): p.27-31.   Cardiovascular manifestations of feline hyperthyroidism were compared in two populations of cats diagnosed at The Animal Medical Center from 1992 to 1993 (n=202) and … Read More

Kraft W. and Buchler F. Tierarztl Prax, 1999. 27: p.386.   20 cases of feline hyperthyroidism are reported. The examinations were performed during 13 years. The hyperthyroid cats were diagnosed of about 23,000 cats examined in two internal veterinary clinics … Read More

Reinartz P., Sabri O., Kinzel S., et al. Nuklearmedizin, 1999. 38(1): p.31-4.   A nine-year-old cat with symptoms of a distinct hyperthyroidism was presented at the University Hospital of the RWTH Aachen. The clinical symptoms as well as the diagnostic … Read More

Reine N.J., Peterson M.E. and Hohenhaus A.E. J Vet Intern Med, 1999. 13: p.245 (abstract). Thrombocytopenia is a rare but well recognized side effect of methimazole (Tapazole) treatment in cats. Methimazole has also been implicated in producing a bleeding tendency … Read More

Ward C.R. Conference Proceedings, (1999). American College of Veterinary Internal Medicine, Chicago, IL: p.557-558   Hyperthyroidism is the most common endocrinopathy in cats, affecting a large percentage of middle to older aged cats. Since its recognition as a clinical entity … Read More

Miyamoto T., Kato M., Kuwamura M., et al. Fel Prac, 1998. 26(5): p.6-9.   A 13-year-old castrated male Persian cat was presented with depression, anorexia, and weight loss. Radiographic and electrocardiographical examinations revealed cardiomegaly and sinus tachycardia. Cardiac ultrasonography indicated … Read More

Hottinger H.A. Conference Proceedings, (1998). American College of Veterinary Internal Medicine, San Diego: p.370   The surgical management of feline hyperthyroidism is associated with many benefits compared to prolonged medical management and a few benefits compared to radioiodine therapy. Surgical … Read More

Kass P.H. Conference Proceedings, (1998). American College of Veterinary Internal Medicine:   The pathologic changes associated with hyperthyroidism (ie, adenomatous hyperplasia and adenoma of the thyroid gland) have been well-characterized in cats, but the pathogenesis of these changes remains unclear. … Read More

Padgett S.L., Tobias K.M., Leathers C.W., et al. J Am Anim Hosp Assoc, 1998. 34(3): p.219-24.   Bilateral thyroidectomy is a commonly indicated treatment for feline hyperthyroidism. The most common postoperative complication is hypocalcemia due to disruption of the parathyroid … Read More

Pearce S.H., Foster D.J., Imrie H., et al. Thyroid, 1997. 7(6): p.923-7.   The characterization of a spontaneous animal model equivalent to a human form of thyrotoxicosis would provide a useful resource for the investigation of the human disorder. Feline … Read More

Merchant S.R. and Taboada J. Vet Clin North Am Small Anim Pract, 1997. 27(6): p.1285-303.   This article focuses on common adrenal and thyroid diseases in the geriatric patient consisting of hypothyroidism in the dog, hyperthyroidism in the cat, and … Read More

Murray L.A. and Peterson M.E. J Am Vet Med Assoc, 1997. 211(1): p.63-7.   OBJECTIVE: To evaluate the efficacy and safety of ipodate in the treatment of hyperthyroidism in cats. DESIGN: Prospective case series. ANIMALS: 12 cats with hyperthyroidism treated … Read More

Singh A.K., Jiang Y., White T., et al. J Vet Diagn Invest, 1997. 9(3): p.261-8.   The performances of a radioimmunoassay method, a chemiluminescent immunoassay method, and a chemiluminescent-enzyme immunoassay method were evaluated for the analysis of cortisol and total … Read More

Lambrechts N., Jordaan M.M., Pilloy W.J., et al. J S Afr Vet Assoc, 1997. 68(2): p.35-9.   Two thyroidal evaluation systems in euthyroid cats (n = 12) were compared. A single, confirmed hyperthyroid cat was included for interest. Firstly, thyroidal … Read More

Adams W.H., Daniel G.B., Legendre A.M., et al. Vet Radiol Ultrasound, 1997. 38(3): p.231-8.   Changes in renal function of twenty-two cats treated for hyperthyroidism using radioiodine were evaluated. Serum thyroxine (T4), serum creatinine, blood urea nitrogen (BUN) and urine … Read More

Jacobs G., Whittem T., Sams R., et al. Am J Vet Res, 1997. 58(4): p.398-403.   OBJECTIVE: To examine the pharmacokinetic profile of propranolol in cats before and during experimentally induced hyperthyroidism. ANIMALS: 8 conditioned, random-source, young adult, female cats. … Read More

Adams W.H., Daniel G.B. and Legendre A.M. Can J Vet Res, 1997. 61(1): p.53-6.   This study evaluated the effects of thyroxine on renal function in the cat. Baseline serum thyroxine (T4) concentrations, clinicopathologic data (complete blood count [CBC], serum … Read More

Archer F.J. and Taylor S.M. Can Vet J, 1996. 37(12): p.735-9.   The effect of hyperthyroidism on serum markers for increased bone metabolism and turnover was evaluated in 36 cats with elevated serum levels of thyroxine and alkaline phosphatase. Serum … Read More

Barber P.J. and Elliott J. J Small Anim Pract, 1996. 37(12): p.575-82.   Thirty cats with untreated hyperthyroidism were blood sampled and their calcium homeostatic mechanisms and renal function assessed. The results were compared with those obtained from 38 age-matched … Read More

Paradis M. and Page N. J Am Anim Hosp Assoc, 1996. 32(6): p.489-94.   Serum free thyroxine (FT4) concentrations using chemiluminescence were measured in hyperthyroid cats (n = 72) and clinically normal cats (n = 129) to establish reference values … Read More

Rush J.E. Conference Proceedings, (1996). International Veterinary Emergency and Critial Care Symposium, San Antonio, TX: p.141-145   Feline hyperthyroidism results from excessive circulating levels of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Hyperthyroidism, the most frequently occurring endocrine disorder … Read More

Mooney C.T., Thoday K.L. and Doxey D.L. Am J Vet Res, 1996. 57(7): p.987-91.   OBJECTIVE: To document circulating total thyroxine (T4) and triiodothyronine (T3) responses after administration of thyrotropin (thyroid-stimulating hormone [TSH]) to hyperthyroid and healthy cats and assess … Read More

Mooney C.T., Little C.J. and Macrae A.W. J Am Vet Med Assoc, 1996. 208(12): p.2004-8.   OBJECTIVE–To determine circulating concentrations and fate of total and free thyroxine (T4) in cats with various illnesses not associated with the thyroid glands (nonthyroidal … Read More

Mooney C. In Practice, 1996. 18(4): p.150-156.   FELINE hyperthyroidism is a frequently encountered disorder with which practitioners are now familiar. Currently, there are three methods of treatment for the hyperthyroid cat. This article looks at the advantages and disadvantages … Read More

Dibartola S.P., Broome M.R., Stein B.S., et al. J Am Vet Med Assoc, 1996. 208(6): p.875-8.   OBJECTIVE–To determine whether increases in BUN and serum creatinine (SCr) concentrations, which have been reported to develop after surgical bilateral thyroidectomy in hyperthyroid … Read More

Forrest L.J., Baty C.J., Metcalf M.R., et al. Vet Radiol Ultrasound, 1996. 37(2): p.141-145.   Hyperthyroidism was diagnosed in 80 cats with thyroid scintigraphy using technetium pertechnetate. These cats were subsequently treated with radioiodine using a modified fixed dose method … Read More

Liptak J.M. Australian Veterinary Practitioner, 1996. 26: p.174-177.   This case report describesa non-functional cystic thyroid adenomain an 1l-year-old, female Siamese.The cat presentedwith a right-sided ventral cervical swelling. Serial serumthyroxine analysis over a l2-month period revealed a euthyroid state. A … Read More

Schumm-Draeger P.M., Langer F., Caspar G., et al. Verh Dtsch Ges Pathol, 1996. 80: p.297-301.   A breeding line of domestic cats spontaneously developing symptoms of hypothyroidism between the 40th and 60th day of life (fur changes, loss of appetite, … Read More

Peterson M.E. and Becker D.V. J Am Vet Med Assoc, 1995. 207(11): p.1422-8.   OBJECTIVE–To evaluate a protocol for subcutaneous radioiodine treatment of cats with hyperthyroidism in which the dose was determined on the basis of severity of the cat’s … Read More

Martin De Las Mulas J., Espinosa De Los Monteros A., Carrasco L., et al. Vet Pathol, 1995. 32(6): p.692-701.   Twenty-eight epithelial and 22 nonepithelial feline tumors were studied immunohistochemically. Epithelial tumors were 10 squamous cell carcinomas, two basal cell … Read More

Norsworthy G.D. Veterinary Medicine, 1995. 90(11): p.1055-1063.   Surgery is a practical method for treating feline hyperthyroidism. But you may be a little unsure of your surgical skills. If so, this modified technique was designed with you in mind.

Guptill L., Scott-Moncrieff C.R., Janovitz E.B., et al. J Am Vet Med Assoc, 1995. 207(8): p.1055-1058.   Summary: Seven cats with thyroid carcinomas that had previously undergone surgical removal of neoplastic tissue were treated with 30 mCi of radioactive iodine … Read More

Parma J., Van Sande J., Swillens S., et al. Mol Endocrinol, 1995. 9(6): p.725-33.   A series of somatic mutations of the TSH receptor gene have been demonstrated in hyperfunctioning thyroid adenomas. The mutations studied up to now cause constitutive … Read More

Cowell R.L. Modern Veterinary Practice, 1985. 13(6): p.309-312. Hyperthyroidism should be considered in cats that eat well yet lose weight. Excessive concentrations of circulating thyroid hormones are usually due to functional thyroid adenomas (adenomatous hyperplasia). However, thyroid carcinomas also occur … Read More

Klein M.K., Powers B.E., Withrow S.J., et al. J Am Vet Med Assoc, 1995. 206(7): p.1007-9.   Of 82 dogs with thyroid carcinoma seen between January 1981 and October 1989, 20 had freely movable tumors without evidence of metastasis and … Read More

Jones B.R., Hodge H. and Davies E. N Z Vet J, 1995. 43: p.23-24.   The cause of hyperthyroidism in cats remains elusive. Clear risk factors for hyperthyroidism other than age have not been identified. The results of this study … Read More

Broussard J.D., Peterson M.E. and Fox P.R. J Am Vet Med Assoc, 1995. 206(3): p.302-5. Hyperthyroidism is the most frequently diagnosed endocnnopathy in cats. The number of cats determined to have hyperthyroidism has increased markedly over the past 10 years, … Read More

Graves T.K., Olivier N.B., Nachreiner R.F., et al. Am J Vet Res, 1994. 55(12): p.1745-9.   We measured glomerular filtration rate (GFR) estimated by plasma disappearance of 99mTc-labeled diethylenetriaminepentaacetic acid, serum concentrations of thyroxine (T4), creatinine, and urea nitrogen, and … Read More

Tarttelin M.F. and Ford H.C. J Nutr, 1994. 124(12 Suppl): p.2577S-2578S. Feline hyperthyroidism was rarely reported until 1979 (Peterson 1984), but is now diagnosed frequently and is considered a common clinical condition in the cat. Hyperthyroidism is usually associated with … Read More

Theon A.P., Van Vechten M.K. and Feldman E. Am J Vet Res, 1994. 55(12): p.1734-8.   One hundred twenty cats with hyperthyroidism were treated with radioiodine (131I); 60 cats were administered radioiodine SC, and 60 cats were administered radioiodine IV. … Read More

Stiles J., Polzin D. and Bistner S.I. J Am Anim Hosp Assoc, 1994. 30(6): p.564-572.   Thirty-six cats with either chronic renal failure or hyperthyroidism were examined. Indirect systemic blood pressure and ophthalmic findings were recorded for each cat. Fifteen … Read More

Rishniw M., Tobias A.H., Marks S.L., et al. J Am Vet Med Assoc, 1994. 205(3): p.425-7. A I3-year-old spayed female domestic shorthair cat was admitted for routine vaccination. The owner was not aware of any problem with the cat at … Read More

Greco D.S. and Harpold L.M. Vet Clin North Am Small Anim Pract, 1994. 24(4): p.765-82.   In conclusion, interaction between the immune and endocrine systems is highly complex. Generally, abnormalities of T suppressor cells, a result of HLA antigen genetic … Read More

Nap A.M., Pollak Y.W., Van Den Brom W.E., et al. J Vet Intern Med, 1994. 8(4): p.302-3.   Thyroidal 99mTcO4- (pertechnetate) uptake percentages were determined in unanesthetized euthyroid (n = 13) and hyperthyroid (n = 18) cats. Maximal uptakes were … Read More

Nemzek J.A., Kruger J.M., Walshaw R., et al. J Am Vet Med Assoc, 1994. 205(1): p.65-8.   Sudden onset of muscular weakness and ventroflexion of the neck were identified in 4 hyperthyroid cats. In each cat, the onset of clinical … Read More

Peterson M.E., Broussard J.D. and Gamble D.A. J Vet Intern Med, 1994. 8(4): p.279-86.   We evaluated serum T4 and T3 concentrations before and after administration of thyrotropin releasing hormone (TRH) in 35 cats with mild to moderate hyperthyroidism, 15 … Read More

Kyle A.H., Tarttelin M.F., Cooke R.R., et al. N Z Vet J, 1994. 42(3): p.101-3.   Excessive or deficient intake of iodine may play a role in the development of goitre and hyperthyroidism in cats. Previous investigations have shown that … Read More

Mooney C. Small Anim Pract, 1994. 35: p.289-294.

Wisner E.R., Nyland T.G. and Mattoon J.S. Vet Radiol Ultrasound, 1994. 35(4): p.310-318.   The ultrasonographic appearance of clinically undifferentiated neck masses for which a definitive diagnosis was eventually obtained in nineteen dogs and one cat is presented in this … Read More

Graves T.K. and Peterson M.E. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.567-76.   Until recently, the diagnosis of hyperthyroidism in cats was thought to be simple; however, not all cases of the disease are straightforward. Although single … Read More

Ferguson D.C. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.515-39.   Until a clinically useful canine TSH assay is available, a valid test of thyroid hypofunction should (1) take into consideration valid (or at least predictive) measurement of … Read More

Kaptein E.M., Hays M.T. and Ferguson D.C. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.431-66.   Knowledge of thyroid hormone and iodide metabolism is derived from a combination of in vivo and in vitro studies in a variety … Read More

Kienle R.D., Bruyette D. and Pion P.D. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.495-507.   Thyroid disease is common in veterinary practice. The heart, especially the myocardium, is sensitive to thyroid hormone, and deficiencies or excesses can … Read More

Kintzer P.P. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.577-85.   Feline hyperthyroidism can be treated with long-term antithyroid drug administration, surgical thyroidectomy, or radioactive iodine. This article discusses the advantages of each of these treatment options and … Read More

Kintzer P.P. and Peterson M.E. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.587-605.   Nuclear medicine may have both diagnostic and therapeutic utility during the evaluation and management of thyroid disease. This article will focus on the use … Read More

Scarlett J.M. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.477-86.   Data regarding the epidemiology of the thyroid diseases in companion animals are sparse. Published studies providing information regarding the epidemiology of canine hypothyroidism and thyroid neoplasia and … Read More

Slater M.R., Komkov A., Robinson L.E., et al. Vet Rad & Ultrasound, 1994. 35(3): p.204-209.   A long-term follow-up study of hyperthymid cats treated with iodine-131 was conducted at the Texas A&M University Veterinary Teaching Hospital. Between January 1985 and … Read More

Welles E.G., Boudreaux M.K., Crager C.S., et al. Am J Vet Res, 1994. 55(5): p.619-27.   Platelet function, antithrombin and plasminogen activities, and fibrinolytic capabilities in 11 cats with acquired heart disease were compared with results in 4 healthy cats. … Read More

Johnson C.A. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.509-14.   Thyroid function and reproductive function have many interactions, the scope and mechanism of which are not fully understood. These functions are of greatest clinical importance for veterinarians … Read More

Jaggy A. and Oliver J.E. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.487-94.   Animals with polyneuropathy associated with primary hypothyroidism have clinical neurologic signs that range from peripheral vestibular signs, lower motor neuronal deficits, laryngeal paralysis, to … Read More

Flanders J.A. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.607-21.   The surgical treatment of thyroid cancer in the cat involves excision of one or both thyroid glands while sparing at least one parathyroid gland. The most common … Read More

Littman M.P. J Vet Intern Med, 1994. 8(2): p.79-86.   Twenty-four cats with spontaneous systemic hypertension were retrospectively studied. Blood pressure (BP) was measured indirectly by the Doppler technique in 17 cats (mean systolic 219.4 +/- 43.2 mm Hg) and … Read More

Horney B.S., Farmer A.J., Honor D.J., et al. Vet Clin Pathol, 1994. 23(3): p.98-102.   Cats with hyperthyroidism [(increased serum thyroxine (T(4)] commonly have increased serum alkaline phosphatase (ALP) activity in addition to other serum biochemical abnormalities. Serum biochemical profiles … Read More

Mooney C.T. J Small Anim Pract, 1994. 35(6): p.289-294.   The efficacy of  radioactive iodine (131I) administration was studied in a series of 50 hyperthyroid cats. The dose administered to each cat was based on the clinical severity of the … Read More

Sansom K.C. J Small Anim Pract, 1994. 35(12): p.604-611.   Between 1990 and 1993, 16 cats were referred with acute onset blindness or intraocular haemorrhage. Blood pressure assessment, using the Doppler ultrasonic recording technique in 11 of the cats, proved … Read More

Wisner E.R., Thèon A.P., Vet M., et al. Vet Radiol Ultrasound, 1994. 35(1): p.53-58.   High-resolution ultrasonography was evaluated as an alternative to 99mTcO-4 scintigraphy for examining size and appearance of thyroid glands in hyperthyroid cats. Thyroid ultrasound examinations were … Read More

Sullivan P., Gompf R., Schmeitzel L., et al. Am J Vet Res, 1993. 54(12): p.2004-9.   Changes in platelet indices (platelet count and platelet size) and PCV associated with thyroid disease were studied in 7 dogs with hypothyroidism and 21 … Read More

Rand J.S., Levine J., Best S.J., et al. J Vet Intern Med, 1993. 7(5): p.272-6.   Spontaneous adult-onset hypothyroidism, confirmed by a thyroid-stimulating hormone stimulation test, thyroid biopsy, and response to replacement therapy, is described in a female cat. Clinical … Read More

Cook S.M., Daniel G.B., Walker M.A., et al. J Vet Intern Med, 1993. 7(5): p.303-8.   Three cats were diagnosed as hyperthyroid based on clinical signs, historical findings, laboratory abnormalities, and basal serum thyroxine (T4) concentrations, and/or nuclear thyroid scans. … Read More

Papasouliotis K., Muir P., Gruffydd-Jones T.J., et al. Res Vet Sci, 1993. 55(1): p.115-8.   Orocaecal transit time was assessed in healthy cats and cats with hyperthyroidism by means of the breath hydrogen test using a standard liquid meal with … Read More

Malik R., Lamb W.A. and Church D.B. Aust Vet J, 1993. 70(6): p.218-9.   Forty cats with hyperthyroidism were treated using 200 to 300 (typically 250) MBq [corrected] of orally administered 131I. Thirty-six cases (90%) were successfully treated, as assessed … Read More

Mcloughlin M.A. J Am Anim Hosp Assoc, 1993. 29(3): p.227-234.   BACKGROUND: Clinical findings indicative of hyperthyroidism are less common in cats with concurrent severe nonthyroidal illness than in cats without concurrent nonthyroidal illness. Nonthyroidal illness (NTI) can lower serum … Read More

Peterson M.E. and Aucoin D.P. Res Vet Sci, 1993. 54(3): p.351-355.   The oral disposition of the antithyroid drugs methimazole and carbimazole were compared in nine clinically normal cats. After the administration of 5 mg of methimazole, serum concentrations of … Read More

Schlesinger D.P., Rubin S.I., Papich M.G., et al. Can J Vet Res, 1993. 57(2): p.89-94.   Orocecal transit time was evaluated in 13 cats diagnosed with hyperthyroidism. Transit was determined by measuring the change in breath hydrogen and methane concentrations … Read More

Craig A. Aust Vet Practit, 1993. 23(1): p.2-6. Feline hyperthyroidism is caused by the overproduction and secretion of thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3) (Bond, 1986; Feldman & Nelson, 1987). It is a disorder affecting mainly middle-aged and old … Read More

Gaschen F., Thompson J., Beale K., et al. American journal of veterinary research, 1993. 54(2): p.244-7.   Serum triiodothyronine autoantibody (T3 AA), triiodothyronine (T3), and thyroxine (T4) concentrations were determined in 45 canine sera containing substantial amounts of thyroglobulin autoantibodies … Read More

Birchard S.J. Feline Practice, 1993. 21(2): p.23-26.   Hyperthyroidism, a multisystem disorder, should be fully understood by the clinician before anesthesia and surgery is attempted. Thyroid tumors in the cat are usually benign and are functional. Malignant thyroid tumors in … Read More

Li X., Steinberg H., Wallace C., et al. Vet Pathol, 1992. 29(6): p.549-51. Follicular cell neoplasia of the thyroid glands occurs most often in domestic cats, dogs, and horses, and infrequently in other animals species. Variable clinical signs of hyperthyroidism, … Read More

Hoenig M., Peterson M.E. and Ferguson D.C. Res Vet Sci, 1992. 53(3): p.338-41.   Glucose tolerance and insulin secretion after administration of a glucose load were determined in 11 clinically normal cats and 15 cats with spontaneous hyperthyroidism. In six … Read More

Thoday K.L. and Mooney C.T. Vet Rec, 1992. 131(12): p.257-64.   The historical and clinical features and the haematological and biochemical changes in 126 cats with hyperthyroidism are described; 125 of the cats were domestic short- or longhaired, and one … Read More

Mooney C.T., Thoday K.L. and Doxey D.L. Journal of Small Animal Practice, 1992. 33: p.228-235.   The efficacy and safety of carbimazole (CBZ) was studied in a series of 45 hyperthyroid cats. CBZ was used before surgical thyroidectomy in 34 … Read More

Watson T., Mooney C.T., Packard C.J., et al. Conference Proceedings, (1992). British Small Animal Veterinary Association:   The plasma lipid transport system is extremely sensitive to modification by the thyroid hormones. This is best illustrated by the changes in plasma … Read More

Mooney C.T. Conference Proceedings, (1992). British Small Animal Veterinary Association: p.168   It has been suggested that the thyrotropin (thyroid stimulating hormone (TSH)) stimulution test may be helpful in confirming a diagnosis of feline hyperthyroidism when the serum total thyroxine … Read More

Peterson M.E. Conference Proceedings, (1992). Proceedings of the feline medicine symposium, held in conjuction with the north american veterinary conference: p.68-71

Hays M.T., Hsu L. and Kohatsu S. Thyroid, 1992. 2(1): p.45-56.   Intestinal absorption of radioiothyroxine (T4*) and of radiotriiodothyronine (T3*) was studied in normal cats (n = 5 for T4* and n = 6 for T3*). Absorption was localized … Read More

Johnson L.A., Ford H.C., Tarttelin M.F., et al. N Z Vet J, 1992. 40(1): p.18-20.   Twenty-eight varieties of commercially-available cat food (23 canned, 5 dried) were analysed for iodine. The iodine concentration varied from less than 0.37 micromol/kg to … Read More

Brown R.S., Keating P., Livingston P.G., et al. Thyroid, 1992. 2(2): p.125-30.   Feline hyperthyroidism bears a strong clinical and pathologic resemblance to toxic nodular goiter in humans. To evaluate whether the observed thyroid growth might be due to circulating … Read More

Graves T.K. and Peterson M.E. Conference Proceedings, (1992). Proceedings of the waltham symposium for the treatment of small animal diseases: endocrinology, 15th annual symposium held in cooperation with the ohio state university: p.97-102

Peterson M.E. Conference Proceedings, (1992). Proceedings of the XVII world congress, world small animal veterinary medical association: p.645-648

Mooney C.T., Thoday K.L., Nicoll J.J., et al. Veterinary Radiology & Ultrasound, 1992. 33(5): p.313-320.   Thyroid imaging using technetium-99m as pertechnetate (99mTcO4) was carried out in five healthy, euthyroid and 37 hyperthyroid cats using both pinhole and parallel-hole collimators. … Read More

Peter H.J., Gerber H., Studer H., et al. Thyroid, 1991. 1(4): p.331-8.   Spontaneous feline hyperthyroidism is a unique experimental model of toxic nodular goiter. To determine whether feline toxic goiter is caused by extrathyroidal stimulating factors or by the … Read More

Trepanier L.A., Peterson M.E. and Aucoin D.P. J Vet Pharmacol Ther, 1991. 14(4): p.367-73.   The pharmacokinetics of methimazole (MMI) administered intravenously and orally were determined in six adult domestic shorthaired cats. There was no significant difference between mean serum … Read More

Eckersall P.D., Mcewan N.A. and Mooney C. Vet Rec, 1991. 129(24): p.532-3.

Refsal K.R., Nachreiner R.F., Stein B.E., et al. J Am Vet Med Assoc, 1991. 199(11): p.1594-601.   Administration of triiodothyronine (liothyronine, 15 micrograms, q 8 h, for 6 treatments) caused marked decrease in serum concentration of thyroxine (T4) and estimates … Read More

Salisury S.K. The Compendium North American Edition, 1991. 13(9): p.1399-1410.   HYPERTHYROIDISM is a common disease of older cats. I. Because of the apparent increased frequency of feline hyperthyroidism in recent years, practitioners should be familiar with the clinical presentation, … Read More

Tribe G.W. Vet Rec, 1991. 129(11): p.252.

Flanders J.A., Neth S., Erb H.N., et al. Am J Vet Res, 1991. 52(8): p.1336-40.   The ability of ectopic parathyroid tissue to support calcium homeostasis was evaluated by measuring serum concentrations of calcium, phosphorus, albumin, magnesium, and parathyroid hormone … Read More

Birchard S.J. Probl Vet Med, 1991. 3(2): p.277-89.   Thyroidectomy has become a fairly common surgical procedure in small animals because of the increasing incidence of thyroid tumors. Surgical removal of the thyroid gland can be routine or quite challenging, … Read More

Jones B.R., Cayzer J., Dillon E.A., et al. N Z Vet J, 1991. 39(2): p.71-4.   Thirty-two elderly domestic shorthaired cats (mean age 12.9 years) were treated with radioiodine (131I). The dose of 131I administered ranged from 39 mBq to … Read More

Tanase H., Kudo K., Horikoshi H., et al. J Endocrinol, 1991. 129(2): p.245-51.   Mutant cats were developed with non-goitrous primary hypothyroidism. They were clinically characterized by severely retarded growth, mild anaemia and high mortality in the young. They responded … Read More

Kintzer P.P. and Peterson M.E. Semin Vet Med Surg (Small Anim), 1991. 6(2): p.131-9.

Stein B.S. Tijdschr Diergeneeskd, 1991. 116 Suppl 1: p.90S-93S.

Peterson M.E. J Vet Intern Med, 1991. 5: p.129.   We recently reported that the triiodothyronine (T3) suppression test is a useful aid in that diagnosis hyperthyroidism in cat, especially when basal serum thyroid hormone concentrations are high normal or … Read More

Sparkes A.H. Journal of Small Animal Practice, 1991. 32: p.59-63. Changes in total thyroxine (T4), free T4 and total tri-Iodothyronine (T3) were measured in 13 cats after the intravenous injection of varying doses of thyrotrophin stimulating hormone (TSH) (0·5 U/cat n … Read More

Boesinger J., Gerber H., Peter H.J., et al. Annales d’endocrinologie, 1991. 52(1): p.59.   Retinoids control cellular differentiation and proliferation; however, the effect appears to be extremely different depending on the tissue.  There are only very few recent studies on … Read More

Trepanier L.A., Peterson M.E. and Aucoin D.P. Res Vet Sci, 1991. 50(1): p.69-74.   The intravenous and oral disposition of the antithyroid drug methimazole was determined in 10 clinically normal cats and nine cats with naturally occurring hyperthyroidism. After intravenous … Read More

Kintzer P.P., Ferguson D.C., Hoenig M., et al. Annales d’endocrinologie, 1991. 52(1): p.87.   Hyperthyroidism is now the most common endocrine disease of the cat and, based on pathologic, immunologic and xenoptransplantation studies, appears similar to toxic nodular goiter.  We … Read More

Graves T.K. and Peterson M.E. Probl Vet Med, 1990. 2(4): p.683-92.   As expertise among small animal practitioners grows, feline hyperthyroidism is being diagnosed earlier in the course of the disease. There are, in fact, a growing number of cats … Read More

Mooney C.T. Vet Rec, 1990. 127(22): p.555.

Trepanier L.A. Probl Vet Med, 1990. 2(4): p.668-82.   Antithyroid drugs are widely used in human medicine for the medical management of Graves’ disease. Because patients with Graves’ disease may undergo spontaneous remission, antithyroid drugs are preferred for long-term therapy … Read More

Peterson M.E. Companion Animal Practice, Japan, 1990. 23: p.42-45.

Peterson M.E. and Gamble D.A. J Am Vet Med Assoc, 1990. 197(9): p.1203-8.   We reviewed the medical records of 494 cats with a variety of nonthyroidal diseases in which serum thyroxine (T4) concentration was determined as part of diagnostic … Read More

Meric S.M. and Rubin S.I. J Am Vet Med Assoc, 1990. 197(5): p.621-3.   The medical records of 62 hyperthyroid cats treated with a fixed dose of 4 mCi of radioactive iodine (131I) were reviewed. In 60 cats, serum thyroxine … Read More

Peterson M.E., Graves T.K. and Gamble D.A. J Vet Intern Med, 1990. 4(5): p.233-8.   The purpose of this study was to develop a T3 suppression test to help in the diagnosis of mild hyperthyroidism in cats. We evaluated the … Read More

Kobayashi D.L., Peterson M.E., Graves T.K., et al. J Vet Intern Med, 1990. 4(2): p.58-62.   The Doppler ultrasonic recording technique was used to measure systolic and diastolic blood pressures indirectly in 28 cats with naturally occurring renal failure, 39 … Read More

Hoenig M., Peterson M.E. and Ferguson D.C. Conference Proceedings, (1990). American College of Veterinary Internal Medicine:

Swalec K.M. J Am Anim Hosp Assoc, 1990. 26(4): p.433-437.   -Retrospective study of 48 hyperthyroid cats that underwent thyroidectomy over a 10 year period. PREDISPOSITIONS. Ages ranged from 6-19 years [mean = 12 years, median = 13 years]. There … Read More

Welches C.D., Scavelli T.D., Matthiesen D.T., et al. Vet Surg, 1989. 18(5): p.392-6.   Bilateral thyroidectomy was performed in 106 cats with hyperthyroidism by one of three techniques: original intracapsular, modified intracapsular, or modified extracapsular. Hypocalcemia was detected in the … Read More

Kaneko M., Kobayashi T., Takano H., et al. Radioisotopes, 1989. 38(8): p.344-6.   Thyroid scintigraphy in rats and mice with 99mTc and 123I was attempted to examine whether this modality might be used in small animals and to describe the … Read More

Kern T.J., Aromando M.C. and Erb H.N. J Am Vet Med Assoc, 1989. 195(3): p.369-73.   The medical records of 74 dogs and 26 cats with Horner’s syndrome (HS) that were admitted to the New York State College of Veterinary … Read More

Sjollema B.E., Pollak Y.W., Van Den Brom W.E., et al. Vet Q, 1989. 11(3): p.165-70.   Thyroidal radioiodine uptake was measured in 10 healthy domestic cats and in 20 hyperthyroid cats. Compared with those in the healthy cats, the uptake … Read More

Taylor J.A., Jacobs R.M., Lumsden J.H., et al. Can Vet J, 1989. 30(6): p.477-481.

Luttikhuis L. Can Vet J, 1989. 30(5): p.437. Hyperthyroidism is the most commonly diagnosed endocrinopathy in the cat. Overproduction of the thyroid hormones, triiodothyronine [T3] and thyroxine [T4], is attributable to thyroid adenoma in more than 95% of cases. Locally an … Read More

Hoenig M. and Ferguson D.C. J Endocrinol, 1989. 121(2): p.249-51.   Intravenous glucose tolerance tests were performed in eight adult cats before and after a 4-week treatment with thyroxine. The untreated cats had a mean fasting blood glucose concentration of … Read More

Christopher M.M. J Am Vet Med Assoc, 1989. 194(8): p.1089-95.   Disease diagnosis, age, sex, and selected hematologic variables were evaluated retrospectively in a population of feline patients with high number of circulating Heinz bodies. By comparing these cats with … Read More

Peterson M.E. and Ferguson D. Conference Proceedings, (1989). American College of Veterinary Internal Medicine: p.123   Clinical study in 8 normal cats and 8 hyperthyroid cats. EXPERIMENTAL DESIGN. Prednisone at 10 mg/cat IM was given to normal and hyperthyroid cats … Read More

Gaitan E., Lindsay R.H., Reichert R.D., et al. J Clin Endocrinol Metab, 1989. 68(4): p.707-14.   Pearl millet [Pennisetum millet (L.) leeke] is the main source of food energy for the rural poor in many areas of the semiarid tropics. … Read More

Ferguson D.C., Peterson M.E. and Nachreiner R.F. J Vet Intern Med, 1989. 3: p.121.   We measured the serum concentrations of total thyroxine (TT4), total triiodothyronine (TT3), reverse T3 (rT3), free T4 (FT4) and T3 (FT3) in 28 normal cats, … Read More

Treppainer L., Peterson M.E. and Aucoin D. Vet Intern Med, 1989. 3: p.125 (abst. #50). Although the antithyroid drug methimazole (MMI; Tapazole) is commonly used in the medical management of cats with hyperthyroidism, pharmacokinetic studies of the drug have not been … Read More

1989/ Recognizing the Clinical Features of Feline Hyperthyroidism Meric S.M. Veterinary Medicine, 1989. 84: p.954-981. The syndrome of feline hyperthyroidism, first recognized just 10 years ago, has become a very common disease in the aging cat population. Small-animal veterinarians can … Read More

Kennedy R.L. and Thoday K.L. Autoimmunity, 1989. 3(4): p.317-8. Hyperthyroidism, although common in Man, is relatively uncommon in other species. The only animal with an appreciable incidence of hyperthyroidism is the domestic cat. Benign thyroid swellings have long been recognised … Read More

Kennedy R.L. and Thoday K.L. Res Vet Sci, 1988. 45(3): p.300-6.   Thyroid autoantibodies have been demonstrated by indirect immunofluorescence in the sera of 10 of 29 (34 per cent) cats with hyperthyroidism. Antinuclear factor, rare in healthy cats, was … Read More

Turrel J.M., Feldman E.C., Nelson R.W., et al. J Am Vet Med Assoc, 1988. 193(3): p.359-64.   The medical records of 14 hyperthyroid cats with thyroid carcinoma were analyzed retrospectively regarding historical, physical, laboratory, and thyroid scintiscan findings, treatment, and … Read More

Ecg of the Month. Sinus Rhythm with Complete Heart Block Jacobs G.J. and Otto C. J Am Vet Med Assoc, 1988. 193(3): p.316-7. A 10-year-old castrated male domestic longhair cat with hyperthyroidism was referred for radioactive iodine (131I) treatment. Treatment … Read More

Peterson M.E., Kintzer P.P. and Hurvitz A.I. J Vet Intern Med, 1988. 2(3): p.150-7.   The efficacy and safety of the antithyroid drug methimazole were evaluated over a 3-year period in 262 cats with hyperthyroidism. In 181 of the cats, … Read More

Peterson M.E., Aucoin D.P., Davis C.A., et al. Res Vet Sci, 1988. 45(1): p.1-3.   The oral and intravenous disposition of the anti-thyroid drug propylthiouracil (PTU) was determined in six clinically healthy cats and four cats with naturally occurring hyperthyroidism. … Read More

Bond B.R., Fox P.R., Peterson M.E., et al. J Am Vet Med Assoc, 1988. 192(11): p.1546-9.   Using M-mode echocardiography, cardiac abnormalities were studied in 103 cats with untreated hyperthyroidism. In addition, follow-up echocardiography was performed on 24 of these … Read More

Labuc R.H. and Jones B.R. N Z Vet J, 1988. 36(2): p.77-81.   Feline hyperthyroidism is the name given to the multisystemic manifestation of excessive concentrations of circulating thyroid hormones, thyroxine (T4) and tri-iodothyronine (T3). The most common cause is … Read More

Hays M.T., Broome M.R. and Turrel J.M. Endocrinology, 1988. 122(6): p.2444-61.   A comprehensive multicompartmental kinetic model was developed to account for the distribution and metabolism of simultaneously injected radioactive iodide (iodide*), T3 (T3*), and T4 (T4*) in six normal … Read More

Scarlett Jm M., Jn Prev Vet Med, 1988. 6: p.295-309.

Broome M.R., Turrel J.M. and Hays M.T. Am J Vet Res, 1988. 49(2): p.193-7. In 76 cats with hyperthyroidism, peak thyroidal radioiodine (131I) uptakes and effective half-lives were determined after administration of tracer and therapeutic activities of 131I. In 6 … Read More

Hays M.T., Turrel J.M. and Broome M.R. J Am Vet Med Assoc, 1988. 192(1): p.7.   Dear Sir: The thyroid hormones, thyroxine (T4) and 3,3′,5- tri-iodothyronine (T3), are known to be tightly bound by plasma pro- teins. It is widely … Read More

Broome M.R., Feldman E.C. and Turrel J.M. J Am Vet Med Assoc, 1988. 192(1): p.49-51.   Serum thyroxine (T4) concentrations of 10 hyperthyroid cats were measured at hourly intervals between 9 AM and 4 PM. In 5 cats, blood samples … Read More

Peterson M.E., Livingston P. and Brown R.S. Vet Immunol Immunopathol, 1987. 16(3-4): p.277-82.   Although feline hyperthyroidism has become a commonly diagnosed disorder of older cats, the underlying etiology remains unknown. Pathological findings of adenomatous hyperplasia involving both thyroid lobes … Read More

Flanders J.A., Harvey H.J. and Erb H.N. Vet Surg, 1987. 16(5): p.362-6. Three bilateral thyroidectomy techniques used in 41 hyperthyroid cats over a 7 year period were compared for rates of postoperative hypocalcemia. Extracapsular dissection of the thyroid glands resulted … Read More

Peterson M.E., Graves T.K. and Cavanagh I. J Vet Intern Med, 1987. 1(3): p.142-6.   We measured serum thyroxine (T4) and 3,3′,5-triiodothyronine (T3) concentrations in hyperthyroid cats (hourly for 10 hours in 14 cats, and daily for 15 days in … Read More

Peter H.J., Gerber H., Studer H., et al. J Clin Invest, 1987. 80(2): p.491-8.   Hyperthyroidism caused by nodular goiters is a common disease of aging cats. Growth and iodine metabolism were studied by autoradiography in normal and hyperfunctioning thyroid … Read More

Broome M.R., Hays M.T. and Turrel J.M. Am J Vet Res, 1987. 48(8): p.1286-9.   The metabolic clearance rate, volume of distribution, and fractional clearance rate of thyroxine (T4), triiodothyronine (T3), and iodide were calculated for 6 healthy and 7 … Read More

Peterson M.E., Kintzer P.P., Cavanagh P.G., et al. J Am Vet Med Assoc, 1983. 183(1): p.103-10.   Hyperthyroidism was diagnosed in 131 cats during a 3 1/2-year period. The cats ranged in age from 6 to 20 years; there was … Read More

Chambers M. The Southwestern Veterinarian, 1987. 38(1): p.37-42. Feline hyperthyroidism Is a recently recognized syndrome of thyrotoxicosis resulting from the hypersecretion of the thyroid hormones, thyroxine (T4), and triiodothyronine (T3I). The syndrome is usually seen in older cats and Is … Read More

Titlbach M., Velicky J. and Lhotova H. Anat Embryol (Berl), 1987. 177(1): p.51-4.   The presence of calcitonin in the cat thyroid was studied immunohistochemically in a series of gland development. The first positive cells are to be found on … Read More

Klausner J.S. Minnesota Journal of Veterinary Medicine, 1987. 27: p.28-32.   Twenty-three hyperthyroid cats were treated with a fixed 5 mCi dose of I-131. In 19 cats, serum thyroxine concentrations were normal following therapy (serum thyroxine concentration = 1.0 to … Read More

Moise N.S., Dietze A.E., Mezza L.E., et al. American Journal of Veterinary Research, 1986. 47(7): p.1476-86.   The echocardiographic, ECG, and radiographic findings of sequentially examined cats with dilatation cardiomyopathy (DCM, n = 7), hypertrophic cardiomyopathy (HCM, n = 8), … Read More

Moise N.S. and Dietze A.E. Am J Vet Res, 1986. 47(7): p.1487-94.   Hyperthyroid cats were examined by electrocardiography, radiography, and echocardiography for the presence of cardiomegaly. These examinations were performed at the time of the initial diagnosis of hyperthyroidism … Read More

Meric S.M., Hawkins E.C., Washabau R.J., et al. J Am Vet Med Assoc, 1986. 188(9): p.1038-40.   Thirty-one cats with hyperthyroidism were given one dose of radioactive iodine (131I) IV. Serum thyroxine (T4) concentrations were measured before treatment in all … Read More

1986/Jan 1 Congestive Heart Failure Associated with Hyperthyroidism in Cats Jacobs G., Hutson C., Dougherty J., et al. J Am Vet Med Assoc, 1986. 188(1): p.52-6.   Hyperthyroidism was diagnosed in 4 cats with congestive heart failure. Dyspnea and anorexia … Read More

Gillen P.L. Vet Med, 1986. 80: p.46-53. An 11-yr-old neutered DSH with bilaterally symmetric alopecia of the pinnae, face, ventral neck, abdomen and back had easily depilated hair and scaly, scabby, pruritic skin The cat was inactive and slept near … Read More

Ferguson D. Feline Health Topics for Vets, 1986. 1(2): p.1-6. The specific cause(s) of feline hyperthyroidism is not known. Spontaneous remission, with out the use of some type of medical or surgical treatment, does not occur. Consequently, the aim of … Read More

Peterson M.E. Carnation Research Digest, 1985. 21: p.1-14.   Hyperthyroidism is a multisystemic disorder resulting from excessive circulating concentrations of the thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Feline hyperthyroidism occurs in the middle- to old-aged cats. There is no … Read More

Peterson M.E. Texas Veterinary Medical Journal, 1985. 47: p.19-25.   Hyperthyroidism (thyrotoxicosis) is a multisystemic disorder resulting from excessive circulating concentrations of the thyroid hormones, thyroxine (T4) and triiodothyronine (T3). Feline hyperthyroidism occurs in middle- to old-aged cats; there is … Read More

Beck K.A., Hornof W.J. and Feldman E.C. Vet Rad & Ultrasound, 1985. 26(1): p.35-38.   A technique for performing thyroid scintigrapy in the cat using technetium 99m pertechnetate is presented. Two groups of cats were studied: group I-five young adult … Read More

Randolph J.F. and Jorgensen L.S. Vet Clin North Am Small Anim Pract, 1984. 14(6): p.1261-70.

Lothrop C.D., Jr., Tamas P.M. and Fadok V.A. Am J Vet Res, 1984. 45(11): p.2310-3.   A canine and feline pituitary-thyroid function test based on thyrotropin-releasing hormone (TRH) stimulation of endogenous thyrotropin is described. Serum thyroxine is measured before and … Read More

Harari J. JAAHA, 1984. 20: p.759-784. A 14-year-old domestic short-haired cat was examined for a recurrent arteriovenous fistula of the left elbow. Hyperthyroidism associated with multinodular adenomatous hyperplasia of the right thyroid gland was also diagnosed. Cardiovascular abnormalities associated with … Read More

Feline Hyperthyroidism Peterson M.E. Vet Clin North Am Small Anim Pract, 1984. 14(4): p.809-26. Hyperthyroidism is a disorder resulting from excessive circulating concentrations of the thyroid hormones, thyroxine (T4) and triiodothyronine (T3) . Normally, circulating concentrations of these hormones lie … Read More

Liu S.K., Peterson M.E. and Fox P.R. J Am Vet Med Assoc, 1984. 185(1): p.52-7.   In a 21/2-year period, hypertrophic cardiomyopathy was found at necropsy of 23 cats that died (13 cats) or were euthanatized (10) because of problems … Read More

Peterson M.E., Birchard S.J. and Mehlhaff C.J. Vet Clin North Am Small Anim Pract, 1984. 14(4): p.911-25. Dogs and cats with underlying endocrine disease are frequently encountered as surgical candidates. The management of animal with diabetes mellitus, hypoadrenoeortieism, hyperthyroidism, hyperadrenoeortieism, … Read More

Kennedy R.L. and Thoday K.L. Vet Rec, 1984. 114(23): p.575.

Gerber H., Peter H., Ferguson D.C., et al. Vet Clin North Am Small Anim Pract, 1994. 24(3): p.541-65.   We have discussed the etiopathology of feline toxic nodular goiter in the context of human nodular goiter pathogenesis. We have reviewed … Read More

Cowen P.N. and Jackson P. Vet Rec, 1984. 114(21): p.521-2.

Turrel JM, Feldman EC, Hays M, et al. J Am Vet Med Assoc, 1984. 184(5): p. 554-9. Eleven cats with hyperthyroidism were treated with radioactive iodine (131I). Previous unsuccessful treatments for hyperthyroidism included hemithyroidectomy (2 cats) and an antithyroid drug … Read More

Peterson M.E., Hurvitz A.I., Leib M.S., et al. J Am Vet Med Assoc, 1984. 184(7): p.806-8.   Nine of 105 cats with hyperthyroidism treated with propylthiouracil developed a serious immune-mediated drug reaction during treatment. Adverse clinical signs, which developed after … Read More

Peterson M.E. and Becker D.V. Veterinary Radiology & Ultrasound, 1984. 25(1): p.23-27.   Thyroid scanning was performed in 135 hyperthyroid cats and 13 normal cats with technetium-99m as pertechnetate (99mTcO4) or with radioactive iodine (131I). Of the hyperthyroid cats, enlargement … Read More

Birchard S.J., Peterson M.E. and Jacobson A. J Am Anim Hosp Assoc, 1984. 20: p.705-709.   The use of thyroidectomy was evaluated as treatment in 85 cats with hyperthyroidism. Based on thyroid scan and surgical findings, 32 cats had a … Read More

Peterson M.E. and Becker D.V. Conference Proceedings, (1983). Proceedings of the 59th annual meeting of the american thyroid association: p.T-31   In 150 aged cats with spontaneous hyperthyroidism, the most frequent clinical signs included weight loss, polyphagia, irritability, tachycardia, polyuria, … Read More

Olsen C. Modern Veterinary Practice, 1983. p.649-652.   Hyperthyroidism in cats can be caused by tumors (often malignant) or cranial mediastinal accessory thyroid tissue. Middle-aged cats with insidious onset of hyperactivity, rough haircoat, weight loss, polyphagia, polyuria and polydipsia are … Read More

Hoenig M. and Ferguson D.C. Am J Vet Res, 1983. 44(7): p.1229-32.   Serum thyroxine (T4) concentrations before and after various IV doses of bovine thyrotropin (TSH) were measured over a 48-hour period in 19 healthy cats. Base-line T4 values, … Read More

Becker D.V. and Peterson M.E. Proceedings of the Annual Veterinary Medical Forum (American College of Veterinary Internal Medicine), 1983. 1: p.p. 40.

Peterson M.E., Kintzer P.P., Cavanagh P.G., et al. J Am Vet Med Assoc, 1983. 183(1): p.103-10.   Hyperthyroidism was diagnosed in 131 cats during a 3 1/2-year period. The cats ranged in age from 6 to 20 years; there was … Read More

Noxon J.O. JAAHA, 1983. 19: p.369-372. Hyperthyroidism is the clinical syndrome that results from hypersecretion of the thyroid hormones, thyroxine (T4 ) and/or triiodothyronine (T3). The wide variety of biochemical abnormalities seen in cats with this disease demonstrates the multisystemic … Read More

Peterson M.E. J Am Vet Med Assoc, 1982. 181(11): p.1434-1436. Vitamin D and parathyroid hormone play important roles in maintaining normal circulating concentrations of calcium and phosphorus. Vitamin D is obtained from dietary sources and produced endogenously from precursors in the … Read More

Peterson M.E. Conference Proceedings, (1982). Proceedings of the Sixth Annual Kal Kan Symposium for the Treatment of Small Animal Diseases (Clinical Endocrinology): p.63-66

Peterson M.E., Keene B., Ferguson D.C., et al. J Am Vet Med Assoc, 1982. 180(8): p.934-7.   Electrocardiographic (ECG) abnormalities were recorded in 36 (80%) of 45 cats with untreated hyperthyroidism caused by hyperfunctioning thyroid adenomas (adenomatous hyperplasia). Tachycardia (greater … Read More

Hoenig M., Goldschmidt M.H., Ferguson D.C., et al. J Small Anim Pract, 1982. 23(1): p.1-12. Hyperthyroidism was diagnosed in 24 aged cats and was characterized by palpable enlargement of the thyroid gland, high circulating levels of thyroid hormones, increased thyroidal … Read More

Mcmillan F.D. Feline Practice, 1981. 11(5): p.25-32.   The following four cases Illustrate the major methods of treatment of feline hyperthyroidism and provide some Insight Into possible sequelae. They are not, however, Intended to provide definitive conclusions regarding the treatment. … Read More

Peterson M.E. J Am Vet Med Assoc, 1981. 179(5): p.485-7.

Watson A.D., Church D.B., Middleton D.J., et al. J Small Anim Pract, 1981. 22(7): p.473-82. Four cats were investigated because they lost weight while eating well. One cat was found found to have hypoinsulinaemic diabetes mellitus, and another has maldigestion caused by … Read More

Jones B.R. and Johnstone A.C. N Z Vet J, 1981. 29(5): p.70-2.

O’brien S.E., Riley J.H. and Hagemoser W.A. Vet Rec, 1980. 107(9): p.199-200.   An aged cat with a thyroid neoplasm showed clinical signs and had laboratory data and post mortem findings similar to those observed in human and canine patients … Read More

Peterson M.E., Becker D.V. and Hurley J.R. Conference Proceedings, (1980). American College of Veterinary Internal Medicine:   Spontaneous hyperthyroidism resulting from toxic nodular goiter was studied in 28 cats aged 9-18 years. Clinical signs included weight loss, polyphagia, nervousness, hyperdefecation, … Read More

Holzworth J., Theran P., Carpenter J.L., et al. J Am Vet Med Assoc, 1980. 176(4): p.345-53.   In ten neutered crossbred cats 10 to 14 years old and of both sexes, hyperthyroidism was evidenced by hyperactivity, weight loss despite increased … Read More

Keene B. and Peterson M.E. J Am Vet Med Assoc, 1980. 176(8): p.712-714. A 13-year-old male castrated domestic short-haired cat was presented for examination because of nervousness, weight loss, polyphagia, voluminous feces, and shortness of breath.

Patnaik A.K. and Lieberman P.H. Vet Pathol, 1979. 16(5): p.687-692.   An 8-year-old castrated, male, domestic short-haired cat had anaplastic giant cell adenocarcinoma in the thyroid gland. The cat had difficulty in breathing and swallowing because of a rapidly growing … Read More

Peterson M.E., Johnson J.G. and Andrews L.K. Conference Proceedings, (1979). American College of Veterinary Internal Medicine, Seattle: p.108   Spontaneous hyperthyroidism due to functional thyroid adenomas was diagnosed in 5 cats ranging in age from 11 to 15 years. Clinical … Read More

Meyer D.J. Vet Clin North Am, 1977. 7(3): p.433-41. The more common clinical manifestations, both the historical and the physical abnormalities, associated with recognized endocrine disturbances in the dog and cat will be discussed . There are few times when … Read More

Leav I., Schiller A.L., Rijnberk A., et al. Am J Pathol, 1976. 83(1): p.61-122. NEOPLASMIS OF THE HUMNAN- THYROID are a well-studied clinical and pathologic entity. Numerous publications have dealt with their histologic classification and biology. Comparable data concerning thyroid … Read More

Mccallum P. Feline Practice, 1974. p.25. Do you have any information on laboratory tests for determination of hypothyroidism and the normal thyroid values in the cat? I also need information on medication and dosage for correction of hypothyroidism. Very little work … Read More

Kallfelz F.A. and Erali R.P. Am J Vet Res, 1973. 34(11): p.1449-1451.

Mason R. and Wilkinson J.S. Aust Vet J, 1973. 49(1): p.44-9.  

Joshua J.O. Vet Rec, 1971. 88(20): p.511-4.

Bustad L.K. and Fuller J.M. Lab Anim Care, 1970. 20(3): p.561-81.

Johnson K.H. and Osborne C.A. J Am Vet Med Assoc, 1970. 156(7): p.906-912. A papillary cystadenocarcinoma of the thyroid gland was encountered in a 20 year-old-spayed female Siamese cat. Attempts to treat the neoplasm by surgical extirpation were unsuccessful. The … Read More

Woods J.W., Wayt H.J. and Baker H.J. Proc Soc Exp Biol Med, 1966. 122(1): p.211-4. Diurnal cycles have been reported in various pituitary-target organ relationships. Evidence that the thyroid may be affected by such rhythms comes from the work of … Read More

Lucke V.M. J Small Anim Pract, 1964. 5(4): p.351-358.   Abstract—The thyroid gland in seventy-five cats has been examined. Abnormalities are by no means uncommon and cases of adenomas, adenomatous goitre, colloid goitre, carcinoma and amyloidosis are described.

Knigge K.M. Anat Rec, 1961. 141: p.151-7. A program of study dealing with neural regulation of thyroid function is being carried out in our laboratory (Knigge and Bierman, ’58; Knigge, ’60a, ’60b, ’61; Florshe and Knigge, ’61). One aspect of … Read More

Meier H. and Clark S.T. Zentralblatt für Veterinärmedizin, 1958. 5(2): p.120-128. In Part I the gross- and histologic lesions in the thyroid of dogs and cats encounted at the Angell Memorial Hospital were reviewed. Patholic alterations were observed to occur … Read More

Holzworth J., Husted P. and Wind A. Cornell Vet, 1955. 45(4): p.487-96. On 15 Sep 1954 a 15-year-old castrated male tabby was admitted at the Angell Memorial Hospital in acute distress. It had been resting quietly shortly before, when it … Read More